Quality Improvement and Practice Based Research in Neurology Using the
Quality Improvement and Practice Based Research in Neurology Using the Electronic Medical Record
What it found
No result yet.
What was tested
Treatment tested
- Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)
What it measured
Main measures
survival free of discontinuation or alternative prevention drug (migraine trial)
six months
survival free of disability measured by FAQ score 9+ (memory trial)
one year
Thinking and memorysurvival free of discontinuation or alternative anti epileptic drug (epilepsy trial)
one year
Who could take part
MS (type not specified) · 18 to 100
Show the full criteria
Inclusion criteria
* Diagnosis of brain tumors, epilepsy, migraine, mild cognitive impairment (concussion), mild traumatic brain injury, multiple sclerosis, neuropathy, Parkinson's disease, restless legs syndrome, and stroke. * Eligible to receive any of the three compared treatments according to FDA approval for the indication or off label use according to standard of care.
Exclusion criteria
-- None
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The investigators will conduct at NorthShore University HealthSystem pragmatic trials using the EMR for 10 common neurological disorders. They will demonstrate the feasibility of subgroup based adaptive assignment of treatments, electronic consenting, and outcomes data capture at the point of care using the EMR. They will identify the most effective treatments for common neurological disorders and seek replication by the NPBRN.
Papers
Background
Maraganore DM, Frigerio R, Kazmi N, Meyers SL, Sefa M, Walters SA, Silverstein JC. Quality improvement and practice-based research in neurology using the electronic medical record. Neurol Clin Pract. 2015 Oct;5(5):419-429. doi: 10.1212/CPJ.0000000000000176.Background
Narayanan J, Dobrin S, Choi J, Rubin S, Pham A, Patel V, Frigerio R, Maurer D, Gupta P, Link L, Walters S, Wang C, Ji Y, Maraganore DM. Structured clinical documentation in the electronic medical record to improve quality and to support practice-based research in epilepsy. Epilepsia. 2017 Jan;58(1):68-76. doi: 10.1111/epi.13607. Epub 2016 Nov 19.
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History
Started
May 2016
Main results due
Dec 2026
Finished
Dec 2027