High Dose Oral Versus Intramuscular Vitamin D3 Supplementation In Mult
Isfahan University of Medical Sciences
What it found
We found no results in the registry or in papers.
This trial finished 11 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Cholecalciferol
Vitamin D receptor agonist
What it measured
Main measures
Serum concentration of 25(OH)D
Two Weeks
How the body handles the medicine
Who could take part
Relapsing MS · 23 to 59
Show the full criteria
Inclusion criteria
* with serum 25(OH)D3 concentration ≤ 20 ng/ml
Exclusion criteria
* hypercalcaemia, primary hyperparathyroidism, Paget disease, thyrotoxicosis, pregnancy, active malignancy, hypercalciuria, history of liver disease, renal insufficiency, clinically apparent malabsorption syndrome, using drugs containing vitamin D products, calcium, estrogen and drugs known to affect vitamin D metabolism (anticonvulsants, glucocorticoids) or receiving any form of supplements containing vitamin D during last 6 months. * Participants with serum 25(OH)D concentration≥ 20 ng/ml
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study aimed to evaluate oral and injectable routes in treatment of hypovitaminosis D in multiple sclerosis (MS) patients. The investigators aimed to assess the efficacy of each method, using the same Mega dose of 600 000 IU D3, in achieving normal serum 25(OH)D level, the durability of the response, the practicality and the possible toxicity.
Papers
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History
Started
Jul 2015
Main results due
Nov 2015
Finished
Dec 2015