High Intensity Interval Training for People With Mild Multiple Sclerosis: A Feasibility Study

CompletedNot a drug-phase studyMS (type not specified)NCT02702804

What it found

No results found

We found no results in the registry or in papers.

This trial finished 9 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • High Intensity Interval Training

What it measured

Main measures

  • Number of participants recruited to the study who adhere to high intensity interval training intervention

    12 months

    Physical functionQuality of life (reported by participants)
  • Number of participants with treatment related adverse events as recorded by the research team

    12 months

    Physical functionSafety

Other measures (2)

  • Physical fitness

    baseline and at 6 weeks which is study completion

    Physical function
  • Impact of treatment intervention on multiple sclerosis

    baseline and at 6 weeks which is study completion

    SafetyQuality of life (reported by participants)

Who could take part

MS (type not specified) · 18 to 65

Show the full criteria

Inclusion criteria

* Clinical Diagnosis of MS more than three months * EDSS score of less than 2.5 * Aged 18-65 * No more than one relapse in the last 2 years * Participants on disease modifying therapy (Interferon and Grateramer Acetate) must have been stable on this treatment for at least 3 months prior to entering the study

Exclusion criteria

* Failure to meet any of the inclusion criteria * Experiencing illness or injury that impairs their ability to be physically active * Living more than 20 miles away from Centre for Sport and Exercise Science

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Exercise has been shown to improve quality of life in people with multiple sclerosis but most exercise programmes are carried out at low to moderate intensities. The next stage in the management of the condition is to establish if people with mild Multiple Sclerosis can exercise, safely and effectively at a higher intensity. High intensity interval training (HIIT) involves repeated bursts of hard exercise interspersed with periods of rest. High intensity interval trainingcould be a time efficient and safe option for people with Multiple Sclerosis. Potential improvements are; cardiovascular fitness, resistance to fatigue, balance, quality of life and attitude to physical exercise. Participants will attend two sessions per week for 6 weeks. Each session will involve 6-10 sets of 60 seconds of high intensity cycling followed by 60 seconds rest. Potential participants must have a clinical diagnosis of Mulitple Sclerosis for more than 3 months, an EDSS score of less than 2.5, aged 18-65, and had no more than one relapse in the last 2 years. From this study the investigators hope to discover if High Intensity Interval Training is a safe and enjoyable form of physical activity for people with mild Multiple Sclerosis. This will then hopefully lead to further large research trials.

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History

    1. Started

      Apr 2016

    2. Main results due

      Nov 2017

    3. Finished

      Nov 2017

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