Cognitive and Emotion Regulation Training in MS
Cognitive and Emotion Regulation Training in Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Mindfulness Meditation
Compared with
- Computerized Cognitive Training
What it measured
Main measures
Change in Reported Engagement After Worry and Rumination Inductions
Baseline and 4 weeks
Other measures (8)
Cognitive Performance on Brief Repeatable Battery (BRB)
Baseline and 4 weeks
Thinking and memoryHeart Rate Variability (HRV)
Baseline and 4 weeks
Daily Emotion Regulation Diary
Baseline and 4 weeks
Improvements on a Self-Report Measure of Emotion Dysregulation
Baseline and 4 weeks
Improvements on a Self-Report Measure of Depression
Baseline and 4 weeks
Mood and sleepImprovements on a Self-Report Measures of Anxiety
Baseline and 4 weeks
Mood and sleepImprovements on a Self-Report Measure of Perceived Stress
Baseline and 4 weeks
Improvements on a Self-Report Measure of Quality of Life
Baseline and 4 weeks
Quality of life (reported by participants)
Who could take part
MS (type not specified) · 30 to 59
Show the full criteria
Inclusion criteria
1. 30-59 years of age 2. Score higher than or equal to 23 on the Mini Mental Status Examination (MMSE) 3. Corrected (near and far) visual acuity of 20/40 or better 4. No previous experience with mindfulness or continuous meditation practice 5. Absence of other co-morbid neurological disorders 6. Relapse free for the last 30 days 7. No use of corticosteroids for the last 30 days 8. Clinically definite diagnosis of MS 9. Ability to use a computer and connect the internet from their home 10. Generation of at least two worries and two ruminations during the daily diary portion of the study for the pre-assessment session
Exclusion criteria
1. Below 30 years of age or above 59 years of age 2. Score lower than 23 on the MMSE 3. Corrected (near or far) visual acuity of 20/40 or greater 4. Previous experience or participation in a mindfulness program 5. Presence of co-morbid neurological disorders such as: * Alzheimers * Parkinson's disease * Dementia 6. Presence of a relapse within the last 30 days 7. Use of corticosteroids within the last 30 days 8. Clinically isolated syndrome suggestive of MS 9. No ability to use a computer and/or a lack of internet connection from their home 10. No self-generated worries and ruminations in the week-long daily diary portion of the study at pre-assessment
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The investigators propose to conduct a randomized feasibility study of mindfulness meditation training (MMT) relative to an active cognitive training control group and waitlist control group in improving emotional regulation in individuals with MS. Individuals will complete pre- and post-assessments of emotional functioning through a week of daily diary entries, as well as self-report measures and a behavioral paradigm. Additionally, all participants will complete an evaluation of neuropsychological functioning, before and after intervention.
Papers
Results
Impact of mindfulness training on emotion regulation in multiple sclerosis: Secondary analysis of a pilot randomized controlled trial.Rehabil Psychol · 2022
Results
Mindfulness training for emotion dysregulation in multiple sclerosis: A pilot randomized controlled trial.Rehabil Psychol · 2020
Results
Effects of 4-week mindfulness training versus adaptive cognitive training on processing speed and working memory in multiple sclerosis.Neuropsychology · 2020
Loading reviews and guidelines…
History
Started
Oct 2015
Main results due
May 2017
Finished
May 2017