Measuring Cerebral Blood Flow Using Pseudo-continuous Arterial Spin Labeling Perfusion Magnetic Resonance Imaging

CompletedNot a drug-phase studyMS (type not specified)NCT02767609

What it found

Results posted, not judged

Results are posted in the registry, but without a statistical test of the main measure. See the numbers below.

What was tested

Treatment tested

  • Magnetic Resonance Imaging

Results by group

Regional Cerebral Blood Flow Values of the Brain Measured Using Pseudo-continuous Arterial Spin Labeling (pCASL) MRI.

single encounter

GroupValueIntervalNumber analysed
Magentic Resonance Imaging35.4 ml/100g/min5.7 (Standard Deviation)1

Values as posted on ClinicalTrials.gov. Outcomes measured differently across trials are not directly comparable.

Safety

GroupParticipants at riskSerious adverse eventsDeaths
Magentic Resonance Imaging10 (0.0%)0

As posted on ClinicalTrials.gov. Serious adverse events include any serious health event during the trial, whether or not the treatment caused it.

What it measured

Main measures

  • Regional Cerebral Blood Flow Values of the Brain Measured Using Pseudo-continuous Arterial Spin Labeling (pCASL) MRI.

    single encounter

    MRI lesions

Who could take part

MS (type not specified) · 18 to 90

Show the full criteria

Inclusion criteria

* Any person between the ages of 18-90 years, who is undergoing routine magnetic resonance imaging (MRI) of the head with or without contrast at Loma Linda University Medical Center. * Must be eligible for MRI (no electronic or metal implants that are not MR compatible).

Exclusion criteria

* Electronic or metal implant that is not MRI safe, pregnancy or claustrophobia.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

This study will test a new MRI sequence that measures cerebral blood flow (CBF). Because this technique for measuring CBF is new, there is little information on what the normal values for different regions of the brain should be. Information from the study will be used to establish normative CBF values for the brain, improving the reliable use of this technique for the diagnosis of brain injury or disease.

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History

    1. Started

      May 2014

    2. Main results due

      Mar 2017

    3. Finished

      Mar 2017

    4. Results posted

      Apr 2019

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