Default Mode Network in Multiple Sclerosis
Study of Default Mode Network (DMN) on Patients With Multiple Sclerosis (MS)
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- neuropsychological battery
- resting state functional magnetic resonance image (rs-fMRI)
What it measured
Main measures
Change of functional connectivity of default mode network (DMN)
at study entry and after 12 months
Nerve conduction tests
Other measures (2)
Correlate grey matter indexes and cognitive functioning indexes
at study entry and after 12 months
Thinking and memoryCorrelate grey matter indexes and emotional/behavioural indexes
at study entry and after 12 months
Who could take part
MS (type not specified) · 18 to 60
Show the full criteria
Inclusion criteria
* MS diagnostic following McDonald 2010 diagnosis criteria. * 18 to 60 years old. * Consent form signature.
Exclusion criteria
* Dementia diagnosis, following Spanish Neurological Society criteria. * Mayor psychiatric illness. * Physical or intellectual limitations to successfully perform - neuropsychological evaluation. * Any other circumstance that may interfere with functional magnetic resonance session. * Abnormal renal function previous to magnetic resonance image (MRI) session.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The study will evaluate connectivity regardless whether patients present a clinical type that requires medical treatment. In this point, investigators will include patients with progressive evolution as well as initial forms of the disease (CIS) and properly established forms of multiple sclerosis (MS) in remittent-recidivant (RR) forms. The researches will not focus on medical treatment as some of these clinical forms have no indication for disease modifying drugs.
Loading reviews and guidelines…
History
Started
May 2017
Main results due
Oct 2021
Finished
Dec 2021