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Dose-Response Effects of Transformative Exercise in Improving Health and Function in Adults With Spinal Cord Injury and Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Movement to Music
What it measured
Main measures
Cardiorespiratory Fitness as measured by sub-maximal VO2
12 weeks
Walking and mobilityPhysical functionPain as measured by PROMIS Pain Interference Short Form 8a
12 weeks
PainFatigue as measured by PROMIS Fatigue Short Form 8a
12 weeks
FatigueGrip Strength as measured by hand grip dynamometer
12 weeks
Arm and hand functionPhysical functionStrength as measured by Biodex System 3 Multijoint dynamometer
12 weeks
Physical functionBalance as measured by the Timed Up and Go
12 weeks
Walking and mobilityBalance as measured by Biodex Limits of Stability
12 weeks
Walking and mobilityBalance as measured by Repeated Chair Stands
12 weeks
Walking and mobilityWalking velocity as measured by the GaitRite
12 weeks
Walking and mobility
Other measures (15)
Health Biomarkers as measured by blood analysis (insulin)
12 weeks
Blood or spinal fluid markersHealth Biomarkers as measured by blood analysis (lipids)
12 weeks
Blood or spinal fluid markersHealth Biomarkers as measured by blood analysis (fasting glucose)
12 weeks
Blood or spinal fluid markersAnthropometric measurements (BMI)
12 weeks
Circumference measurements to be reported as composite ratios (waist circumference, hip circumference, neck circumference)
12 weeks
Physical Function with Mobility Aid as measured by PROMIS Physical Function with Mobility Aid 455b
12 weeks
Walking and mobilityAnxiety as measured by PROMIS Emotional Distress-Anxiety Short Form 8a
12 weeks
Mood and sleepDepression as measured by PROMIS Emotional Distress-Depression Short Form 8a
12 weeks
Mood and sleepSleep Disturbance as measured by PROMIS Sleep Disturbance Short Form 8a
12 weeks
Mood and sleepAbility to participate in social roles and activities as measured by PROMIS Ability to Participate in Social Roles and Activities Short Form 8a
12 weeks
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* Diagnosed with stroke * MS - mild to moderate disability (Patient Determined Disease Steps Score 0-6) * Able to use arms or arm/legs for exercise * Ambulatory or use manual wheelchair
Exclusion criteria
* Cognitive impairment (Mini-Mental State Exam score \< 24) * Recent weight change (+/- 25 pounds in 1 year) * Poorly controlled blood pressure * Cardiovascular disease event within the past six months * Severe pulmonary disease * Renal failure * Current tobacco user or quit within the last six months * Current use of medications for psychosis * Active pressure ulcers
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The specific aim of the study in our example is to conduct a feasibility translational home-based exercise trial established in the LEADERS (R2) project with the TExt-ME tele-exercise training system for participants with neurologic disability. We hypothesize that participants in this home-based tele-exercise training program will achieve similar gains in health and function outcomes as the onsite exercise training program. Further, there will be no difference in adverse side effects (safety) between the home-based and onsite exercise treatment groups.
Papers
Loading reviews and guidelines…
History
Started
Feb 2017
Main results due
May 2019
Finished
May 2019