Armergometry to Improve Mobility in Chronic Progressive Multiple Sclerosis

Status unknownNot a drug-phase studyProgressive MSNCT03147105

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • arm ergometry

What it measured

Main measures

  • 6 minute walking test

    6 min.

    Walking and mobility

Other measures (5)

  • accelerometry

    7 days

    Walking and mobility
  • verbal learning and memory

    30 minutes

    Thinking and memory
  • peak oxygene uptake

    20 minutes

  • brain atrophy

    3 months

    Brain volume loss
  • Brain derived neurotrophic factor

    3 months change

Who could take part

Progressive MS · 18 to 60

Show the full criteria

Inclusion criteria

* proven multiple sclerosis * stable disease * EDD 4,0-6,5 * being able to perform arm ergometry

Exclusion criteria

* relapse situation * cognitive deficit unable to understand study * cardivascular disease * contraindication for MRI

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Chronic progressive multiple sclerosis patients will be randomised to home-based arm ergometry training for 12 weeks or a waitlist control group which will have access to the treatment after 12 weeks when primary endpoint assessment has been obtained. Assessments include clinical outcomes and questionnaires as well MRI imaging and transcranial magnetic stimulation paradigms. Primary endpoint will be the 6 minute walking test at week 12.

Papers

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History

    1. Started

      May 2017

    2. Main results due

      Jul 2018

    3. Finished

      Dec 2018

    Assembled by software from public sources.