Effects of Yoga Practice in Multiple Sclerosis Patients: a Multidimensional Approach

Running, not recruitingNot a drug-phase studyMS (type not specified)NCT03198598

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Iyengar Yoga
  • Yoga app

What it measured

Main measures

  • Improvement of overall MS impact in patients life

    3 months

    Quality of life (reported by participants)
  • Cognition in MS

    3 months

    Thinking and memory
  • Fatigue in MS

    3 months

    Fatigue
  • Self-efficacy in MS

    3 months

Other measures (10)

  • Cyytokine levels

    3 months

    Immune response
  • Correlation between gait and hemodynamic response

    3 months

    Walking and mobility
  • Motor agility

    3 months

    Disability progression
  • Awareness and attention

    3 months

    Thinking and memory
  • Lymphocyte B activity

    3 months

    Immune response
  • Walking speed

    3 months

    Disability progressionWalking and mobility
  • Ability to stand up and walk

    3 month3

    Walking and mobility
  • Hands strenght

    3 months

    Arm and hand function
  • Self-compassion

    3 months

  • Affects

    3 months

Who could take part

MS (type not specified) · 18 to 60 · EDSS 0 to 8

Show the full criteria

Inclusion criteria

* Multiple Sclerosis patients from 18 to 60 years of age, currently in stable immunomodulatory or immunosuppression therapy with no signs of clinical or radiological disease activity for the last 6 months. * EDSS from 0 to 8

Exclusion criteria

* presents clinical or radiological disease activity for the last 6 months * no cognitive capacity to understand the written informed consent form

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

In this study the investigators will evaluate the effects of yoga practice on multiple sclerosis patients and healthy controls for fatigue, quality of life, movement, cognition, brain activity, self-efficacy, stress, anxiety, depression, affective states and immunological response. To investigate the effects of yoga training delivered by a yoga instructor or through a smartphone application, the investigators will use a multidimensional approach that comprises of: evaluation of neuropsychological, quality of life and affective aspects, structural and functional magnetic resonance imaging, functional near infrared spectroscopy (fNIRS) combined with movement analysis (gait, strength, balance etc.) and analysis of the immune response.

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History

    1. Started

      Jun 2017

    2. Main results due

      Dec 2026

    3. Finished

      Dec 2026

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