Stylistic Memory Enhancement

CompletedNot a drug-phase studyMS (type not specified)NCT03206034

What it found

No results found

We found no results in the registry or in papers.

This trial finished 10 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Stylistic Memory Enhancement

What it measured

Main measures

  • California Verbal Learning Test (CVLT-II- Total learning

    Baseline and post-intervention (5 weeks between testing sessions)

Other measures (1)

  • Memory Functioning Questionnaire

    Baseline and post-intervention ( 5 weeks between testing sessions)

    Thinking and memory

Who could take part

MS (type not specified) · 18 to 59

Show the full criteria

Inclusion criteria

Clinically definite MS between the ages of 18 and 59. Participants must have impairment in new learning (determined by an in-person screen) with intact language comprehension.

Exclusion criteria

* History of alcohol or drug abuse/dependence, * Major psychiatric disturbance (e.g. bipolar disorder, schizophrenia) and neurological history other than MS. * Corticosteroid use within the last month prior to the participation. * Less than 1 month post most recent exacerbation.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Impairments in higher level cognitive processing, such as new learning and memory, are common in Multiple Sclerosis (MS) and negatively impact multiple aspects of everyday life, including occupational and social functioning. Despite this, few studies have attempted to remediate these cognitive deficits in order to improve everyday functioning. While not applied in traditional rehabilitation protocols as of yet, many techniques from cognitive psychology significantly improve learning and memory in healthy persons. These techniques include the generation effect (GE), the spacing effect (SE), and the testing effect (TE). These techniques have recently been incorporated into an 8-session treatment protocol, Stylistic Memory Enhancement (SME), designed to teach participants about each of the techniques, train them on how to apply the techniques in daily life and practice their application to daily life memory demanding situations. The protocol includes teaching participants how to restructure a memory demanding situation in order to make optimal use of self-generation, spaced learning and self-testing. The objective of the study is to test the efficacy of the SME in an MS population.

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History

    1. Started

      Mar 2013

    2. Main results due

      Dec 2015

    3. Finished

      Dec 2015

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