Efficacy of Lower Limb Exercises on Overactive Bladder Symptoms in Pat
Efficacy of Isometric Contraction Exercises of Lower Limbs Muscles, in Modulating Neurological Control of Bladder Function in Patients With Multiple Sclerosis
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Usual physical therapy+ strengthening of lower limbs muscles
- Usual physical therapy
What it measured
Main measures
Change of Urinary frequency
at 6th and 22nd day
Bladder, bowel and sexual functionChange of Urge score
at 6th and 22nd day
Change of total score of OAB-q ( Overact Bladder questionnaire) long form
at 3rd and 18th day
Bladder, bowel and sexual functionQuality of life (reported by participants)
Other measures (11)
Change of Urine volume
at 6th and 22nd day
Bladder, bowel and sexual functionChange of episodes of urinary incontinence
at 6th and 22nd day
Bladder, bowel and sexual functionChange of episodes of nocturia
at 6th and 22nd day
Bladder, bowel and sexual functionChange of Postvoid Residual Volume
at 3rd and 18th day
Bladder, bowel and sexual functionChange of Pad-test 24 Hours
at 6th and 22nd day
PGI (Patient global impression of improvement)
at 18th day
Bladder, bowel and sexual functionChange of value at Uroflussimetry
at 3rd and 18th day
Bladder, bowel and sexual functionChange of value at "H REFLEX" test
at 6th and 22nd day
Change of EDSS (Expanded Disability Status Scale)
at 2nd and 22nd day
Disability progressionChange of Barthel Index Score
at 2nd and 22nd day
Who could take part
MS (type not specified) · 18 to 80
Show the full criteria
Inclusion criteria
* Multiple Sclerosis Patients * Urge score >=2 * urinary daytime frequency >=8 * stable overactive bladder symptoms for 6 months * MRC ( Medical Research Council) scale of ankle plantarflexors and hamstrings >=2 * signed informed consensus
Exclusion criteria
* FIM ( Functional Independence Measure) memory items \<=4 * impairment in registering bladder diary * inclusion in other experimental study * specific straightening during the suty period * PVR >= 200 ml ina single evaluation or PVR (post void residual) >=150 in 4 evaluation (twice a day for 2 consecutive days) * Urinary infections * concomitant urological disease * intrathecal baclofen pump * SANS (Stoller Afferent Nerve Stimulation) * modification of therapy for overactive bladder symptoms within three months before entering the study
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The aim of the study (OVERACT_V1) is to verify if the isometric contraction of ankle plantarflexor and Hamstring muscles, induces a significant reduction of overactive bladder symptoms in patients with Multiple sclerosis.
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History
Started
Feb 2018
Main results due
Feb 2020
Finished
Feb 2020