Effects of Inspiratory Muscle Training in Persons With Advanced Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT03345199

What it found

No results found

We found no results in the registry or in papers.

This trial finished 7 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Inspiratory Muscle Trainer (IMT)

What it measured

Main measures

  • Change in Maximal inspiratory Pressure (MIP)

    Baseline to 28 weeks

    Physical function
  • Change in Maximal Expiratory Pressure (MEP)

    Baseline to 28 weeks

    Nerve conduction tests

Other measures (3)

  • Change in Fatigue

    Baseline to 28 weeks

    Fatigue
  • Change in Activity Participation

    Baseline to 28 weeks

  • Change in Respiratory Infection Incidents

    Baseline to 28 weeks

Who could take part

MS (type not specified) · 18 and over

Show the full criteria

Inclusion criteria

* Residents of The Boston Home * Diagnosis of multiple sclerosis by a physician * Expanded Disability Status Scale >6.5 * Able to follow instructions in English

Exclusion criteria

* Hospitalization for exacerbation of MS within the previous 2 months * Unstable heart, lung, or other physical conditions * Current smoker * Oral temperature greater than 100 degrees Fahrenheit * Acute illness, such as infection, inflammation, ongoing chest pain, or short of breath with light activities * Current neurological diseases other than MS

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

This study evaluates the effects of a 10-week inspiratory muscle training on the outcomes of respiratory muscle strength, fatigue, activity participation, and respiratory infection rates in persons with advanced Multiple Sclerosis (MS). Participants will perform daily exercise using the Threshold Inspiratory Muscle Trainer (IMT) device during the training period. The study will assess whether the participants improve after the training, and whether the effects can be maintained after the training ends.

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History

    1. Started

      Oct 2017

    2. Main results due

      Dec 2018

    3. Finished

      Apr 2019

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