Randomized Controlled Trial of Core Stability Training in Patients With Multiple Sclerosis: Biomechanical and Performance Based Analysis of Gait

CompletedNot a drug-phase studyMS (type not specified)NCT03442049

What it found

No results found

We found no results in the registry or in papers.

This trial finished 10 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Physiotherapy - Study group

Compared with

  • Physiotherapy - control group

What it measured

Main measures

  • 6 Minutes Walk Test

    Change from Baseline 6 Minutes Walking Distance at 6 weeks.

    Walking and mobility
  • Modified Borg Scale

    Change from Baseline Fatigue Score at 6 weeks.

    Fatigue
  • Plantar Pressure Distribution

    Change from baseline peak pressure and contact area values at 6 weeks

  • Multiple Sclerosis Quality of Life Scale

    Change from baseline mental and physical quality of life scores at 6 weeks

    Quality of life (reported by participants)

Other measures (3)

  • Muscle strength with hand held dynamometer

    Change from baseline muscle strength at 6 weeks

    Physical function
  • MiniBESTest

    Change from baseline MiniBESTest scores at 6 weeks

    Walking and mobility
  • Dynamic Gait Index

    Change from baseline Dynamic Gait Index scores at 6 weeks

    Walking and mobility

Who could take part

MS (type not specified) · 18 and over · EDSS 3 to 5

Show the full criteria

Inclusion criteria

* Older than 18 years old * EDSS score is between 3-5,5 * Patients who did not take corticosteroid therapy within three months * Patients who get at least 24 points from the Mini Mental Test were included in the study.

Exclusion criteria

* Patients who had an acute MS attack or had an attack within the last three months. * An orthopedic or systemic problem that would prevent participation in exercises * Patients who were using walking orthoses or walking aids were not included in the study.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Gait and mobility are among the functions frequently affected in Multiple Sclerosis (MS) and have a negative impact on quality of life. Strength losses in lower limb muscles, ataxia, sensory problems and fatigue are the most important reasons of walking problems in patients with MS. In addition to loss of strength and tonus problems, especially biomechanical disorders can be seen on foot and this problem affects gatin and balance negatively. The stabilizing muscles, defined as the "core" region and enveloping the body like a corset, are active in the context of postural preparation prior to lower extremity movements and stabilize for the limb movements to be performed. The aim of this study was to investigate the effects of spinal stabilization exercises on walking performance, fatigue, plantar pressure distribution, balance, muscle strength and quality of life in patients with Multiple Sclerosis.

Papers

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History

    1. Started

      Jan 2015

    2. Main results due

      Feb 2016

    3. Finished

      May 2016

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