The Effects of Clinical Pilates Training on Walking, Balance, Fall Risk, Respiratory and Cognitive Functions in Persons With Multiple Sclerosis: A Randomized Controlled Trial

CompletedNot a drug-phase studyMS (type not specified)NCT03502772

What it found

No results found

We found no results in the registry or in papers.

This trial finished 8 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Pilates exercises

Compared with

  • Home exercise program

What it measured

Main measures

  • 12-Item MS Walking Scale

    Change from Baseline at 8 weeks

    Walking and mobility

Other measures (15)

  • Six-Minute Walk Test

    Change from Baseline at 8 weeks

    Walking and mobility
  • Timed 25-Foot Walk

    Change from Baseline at 8 weeks

    Disability progressionWalking and mobility
  • Timed-Up and Go

    Change from Baseline at 8 weeks

  • Limits of Stability Test

    Change from Baseline at 8 weeks

  • Postural Stability Test

    Change from Baseline at 8 weeks

  • Fall Risk Index

    Change from Baseline at 8 weeks

    Walking and mobility
  • Falls Efficacy Scale-International

    Change from Baseline at 8 weeks

    Walking and mobility
  • Activities-Specific Balance Confidence Scale

    Change from Baseline at 8 weeks

    Walking and mobility
  • Curl-up Test

    Change from Baseline at 8 weeks

  • Maximum Inspiratory Pressure

    Change from Baseline at 8 weeks

    Physical function

Who could take part

MS (type not specified) · 18 and over

Show the full criteria

Inclusion criteria

* a diagnosis of definite MS * an age over than 18 years * walking independently 100 meters * willingness to participate in the study

Exclusion criteria

* any neurological disease other than multiple sclerosis * relapse within 3 months * having orthopaedic disorders that could negatively affect gait and balance * having cardiopulmonary disorders * diagnosed cognitive and psychiatric problems * current and recent (within the last 6 months) participation in a core stability based exercise program

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Multiple sclerosis (MS) is a chronic-progressive and neurodegenerative disease. Thus, exercise programs are needed to maintain and increase functional status of persons with MS (pwMS). Pilates exercises designed by physiotherapist can enhance participation and functionality in pwMS. The aim is to investigate the effects of a clinical Pilates training on balance, walking, fall risk, respiratory and cognitive functions in pwMS. Forty-two pwMS will be included in this randomized controlled trial. Participants will be divided into two groups with stratified randomization. Pilates exercises group (n=21) will receive therapy once a week for 8 weeks plus home exercise programme. The home exercise program group (n = 21) will be given written exercises that matched the aims of the Pilates exercises and the program compliance will be monitored by telephone calls once a week. The assessments will be done twice at the beginning and at the end of the treatment. The outcome measures include the Timed 25-Foot Walk (T25FW), Six-Minute Walk Test (6MWT), Timed Up and Go (TUG), TUG cognitive and manual forms, 12-Item Multiple Sclerosis Walking Scale (MSWS-12), Curl-Up Test (CUT), Falls Efficacy Scale-International (FES-I), Activities-specific Balance Confidence (ABC) Scale, respiratory muscle strength assessment, Brief International Cognitive Assessment for MS (BICAMS).

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History

    1. Started

      Apr 2017

    2. Main results due

      Dec 2017

    3. Finished

      Dec 2017

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