Motor Evoked Potentials With Modified Facilitation Technique: Normative Data and Reliability in Healthy Individuals and Comparison of Sensitivity and Specificity With Standard Technique in Patients With Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT03646929

What it found

No results found

We found no results in the registry or in papers.

This trial finished 7 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • MEP using standard facilitation technique
  • MEP using modified facilitation technique

What it measured

Main measures

  • Change in Test- Re-Test reliability when using modified facilitation technique (compared to standard facilitation technique) in healthy individuals

    measuring time 2 (75 minutes) maximal 1 month later than measuring time 1 (75 minutes)

  • comparison of sensitivity and specificity of modified facilitation technique and standard facilitation technique in patients with multiple sclerosis

    1 measuring time (90 minutes)

Who could take part

MS (type not specified) · 18 to 65

Show the full criteria

Inclusion criteria

Inclusion Criteria for healthy individuals: * Ability to understand the purpose and risks of the study, provide signed and dated informed consent * Between 18 and 65 year of age * No neurologic or psychiatric comorbidity requiring continous treatment * No previous damage of central nervous System Inclusion Criteria for patients: * Ability to understand the purpose and risks of the study, provide signed and dated informed consent * Between 18 and 65 year of age * patients with inflammatory diseases of the central nervous system (CNS) or multiple sclerosis appointed for routine MEP diagnostic at the Department of Clinical Neurophysiology, University Hospital Basel

Exclusion criteria

* Contraindication for measuring of motoric evoked potentials (MEP): metal implants (pacemaker, stents); known epilepsy oder previous epileptic fit * Known disease of the peripheral nervous system (polyneuropathy)

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Investigating the change in Test- Retest- reliability in healthy individuals when applying a modified easy to use facilitation technique compared to standard facilitation technique and analyzing sensitivity and specificity in patients with multiple sclerosis regarding detection of pathologic results

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History

    1. Started

      Dec 2017

    2. Main results due

      Jan 2019

    3. Finished

      Jan 2019

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