Photobiomodulation Therapy in Persons With Multiple Sclerosis
Effect of Photobiomodulation Therapy on Muscle Function and Inflammation in Persons With Multiple Sclerosis
What it found
We found no results in the registry or in papers.
This trial finished 7 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Photobiomodulation Therapy
Placebo
- Placebo
What it measured
Main measures
Muscle Fatigue
up to 4 week photobiomodulation intervention, immediately after the intervention, and then 4 months after this extended treatment
Fatigue
Other measures (1)
Systemic Inflammation
up to 4 week photobiomodulation intervention, and then again at 4 months post-intervention
Immune response
Who could take part
Relapsing MS · 20 to 60
Show the full criteria
Inclusion criteria
1. Relapsing remitting MS, 2. Independent or ambulatory with minimal aid. 3. Must be able to move foot (ankle dorsiflexion) at least moderately forcibly against gravity (manual muscle test score 3-5) 4. Subjects must be able to walk for 6 minutes independently with no or minimal use of an assistive device.
Exclusion criteria
1. No noticeable left right ankle strength asymmetry 2. No exacerbations (MS attacks) or immunosuppressive therapy use within the previous 6 months 3. No concurrent infection or known cardiovascular disease including having a pacemaker; or other serious medical co-morbidity including metabolic, mitochondrial, autoimmune, diseases or other co-existing neurologic conditions. 4. Not involved in any clinical trial or other research that could confound results. 5. Must not be pregnant 6. Must not have an active diagnosis of cancer
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study will test whether photobiomodulation therapy improves muscle endurance and decreases inflammation in persons with relapsing-remitting multiple sclerosis. We will also investigate mechanisms for any improvements.
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History
Started
Apr 2018
Main results due
Sept 2019
Finished
Sept 2019