Periodized Rehabilitation and Beta-alanine Supplementation in Multiple
Periodized Rehabilitation and Beta-alanine Supplementation in Multiple Sclerosis
What it found
We found no results in the registry or in papers.
This trial finished 6 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Beta-alanine
Given to everyone in the trial
- Classic, progressive endurance training
- Periodized exercise training
What it measured
Main measures
Exercise capacity
3 weeks
FatiguePhysical functionSerum lactate
3 weeks
Physical functionBody composition
3 weeks
Physical functionBody mass index
3 weeks
Strength measurement
3 weeks
Physical functionMuscle carnosine concentration
3 weeks
Who could take part
MS (type not specified) · 18 to 75
Show the full criteria
Inclusion criteria
* Diagnosis Multiple Sclerosis. * Healthy control. * Aged >18y. * Written informed consent.
Exclusion criteria
* Contraindications to perform moderate to high intensity exercise. * Participation in another study. * Experienced acute MS related exacerbation \<6 months prior to start of the study * EDSS score > 6
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Exercise therapy and increased physical activity in persons with Multiple Sclerosis (MS) improves mobility, muscular strength, physical fitness and fatigue without increasing relapse rate. As such, physical activity and more particular exercise therapy have become an important part of MS rehabilitation. Despite the fact that the positive effects of exercise therapy in MS are obvious only 43 percent of the MS community reports to participate in an exercise program4. Therefore, new exercise therapy approaches that further optimize rehabilitation, improve exercise adherence and promote participation in physical exercise in MS are interesting to explore. Therefore, the randomized controlled trial investigates two types of exercise interventions (classic progressive vs periodized) with or without the addition of ergogenic supplements (beta-alanine vs placebo).
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History
Started
Jan 2019
Main results due
Dec 2019
Finished
Dec 2019