An Investigation of Upper Extremity Function in Patients With Multiple Sclerosis, and Its Relation With Shoulder Position Sense and Disability Level

CompletedNot a drug-phase studyMS (type not specified)NCT03846336

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Upper extremity function
  • Shoulder position sense

What it measured

Main measures

  • Upper extremity function

    1 month

    Disability progressionArm and hand function

Other measures (1)

  • Shoulder position sense

    1 month

Who could take part

MS (type not specified) · 18 to 60

Show the full criteria

Inclusion criteria

* Clinical diagnosis of Multiple Sclerosis Disease * The level of disability should be between 0.5-4 according to EDSS

Exclusion criteria

* Patients with acute attacks (three months prior to the study) * Mini-Mental State Examination (MMSE) score of less tahn 25 points * History of shoulder injury, surgery, medical problems or other neurological disorders in any of the participants

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The purposes of this study is to investigate the relationship between upper extremity muscle function and shoulder position sense in patients with Multiple Sclerosis (MS) and which best projects the disability status. Upper extremity dysfunction is considered to be the main cause of the loss performance of activities of daily living and this problem was include all motor and somatosensory components of function. Any failure in each of these components will likely create an impairment in the normal function. One of the most important components of the somatosensory system is joint position sense, a sub-modality of proprioception. Position sense disorders are seen from the early stages of the disease and upper extremity function problems is experienced depending on position sense disorders in patients with MS. Expanded Disability Status Scale (EDSS) is one of the most commonly outcome measures in evaluating the level of disability in MS population. Because EDSS scale emphasis on ambulation, so it is insensitive to upper extremity function. But the ability to use walking aids (e.g., canes, walkers, wheelchairs, etc.) may be affected by the UE impairment so shoulder position sense. When literature is examined, there is no study which examines the relationship between upper extremity muscle function and shoulder position sense in patients with Multiple Sclerosis and which best projects the disability status. For all these reasons, we think that shoulder position sense is changed both dominant and non-dominant side during flexion and abduction movements in mild-moderate MS patients and that these deficits are correlated with upper extremity function and disability level.

Papers

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History

    1. Started

      Jun 2018

    2. Main results due

      Jul 2018

    3. Finished

      Sept 2018

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