Behavioural Activation for Low Mood in Multiple Sclerosis
Behavioural Activation for Low Mood in Multiple Sclerosis
What it found
We found no results in the registry or in papers.
This trial finished 7 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Behavioural Activation
What it measured
Main measures
Change in depression: Hospital Anxiety and Depression Scale; Zigmond & Snaith, 1983
Screening, Baseline, Week 1, Week 2, Week 3, Week 4, Week 5, Week 6, Week 7, Week 8, Week 9, Week 10, Week 11, Week 12
Mood and sleep
Other measures (3)
Changes to fatigue: Modified Fatigue Impact Scale; Vickrey et al., 1995
Baseline, Week 6, Week 12
Thinking and memoryFatigueQuality of life (reported by participants)Changes to quality of life: Health Status Questionnaire Short form version 2. SF-12v2; Ware, Kosinski, & Keller, 1996
Baseline, Week 6, Week 12
Quality of life (reported by participants)Changes in behaviour associated with depression: The Behavioural Activation for Depression Scale Short Form
Day 1, day 3, day 5, day 7, day 9, day 11, day 13, day 15, Week 3, Week 4, Week 5, Week 6, Week 7, Week 8, Week 9, Week 10, Week 11, Week 12
Mood and sleep
Who could take part
Progressive MS · 18 and over
Show the full criteria
Inclusion criteria
* Clinical diagnosis of Secondary Progressive Multiple Sclerosis * Must speak English * Must have capacity to give consent * Must have a telephone * Must have access to the internet * Must be able to use a computer * Must score ≥ 8 on the Hospital Anxiety and Depression Scale - depression subscale
Exclusion criteria
• Receiving psychological therapy for a pre-existing mood problem.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Title: Behavioural Activation for Low mood in Multiple Sclerosis The study will be sponsored by the University of Lincoln, indemnity will be provided by U M Association Limited. Depression is highly prevalent among people with Multiple Sclerosis (MS). More specifically, as the disease progresses, people are more likely to develop depression and there is limited evidence of suitable interventions in this group. There are few studies that investigate the most appropriate duration, delivery modality, or individual adaptations for therapy for people with secondary progressive Multiple Sclerosis. This is problematic because continued reduction in physical and cognitive ability, combined with greater incidence of depression, may make accessing and engaging in therapies difficult. Behavioural activation is a technique used as a component of psychotherapy. Behavioural activation aims to reduce behaviours that maintain or exacerbate depression by promoting counteracting behaviours, using strategies such as activity monitoring and scheduling. However, there is no research looking in-depth at the underlying processes. Therefore, this research aims to explore the feasibility and efficacy of behavioural activation by: * Adapting an existing behavioural activation manual into five sessions, suitable for people with secondary progressive MS. * Examining if behavioural activation is followed by phases of change that are considered to predict later therapeutic outcome and to determine whether behavioural activation accounts for changes observed. Up to ten participants from Nottingham University Hospitals will be recruited. Participants will be briefed on the research aims and consent will be obtained before commencing the intervention. The project will follow a multiple baseline single-case experimental design. Participants will complete weekly outcome measures that aim to observe low mood, quality of life, and adherence to behavioural activation and alignment with individual's values. Following five to six contact sessions, participants will take part in a follow-up interview. Participants will then be debriefed.
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History
Started
Mar 2019
Main results due
Jun 2019
Finished
Jun 2019