Intermittent vs Continuous Walking in People With Multiple Sclerosis
Intermittent vs. Continuous Walking Training in People With Multiple Sclerosis: a Comparison of Effectiveness
What it found
No result yet.
Reason given: COVID-19 Pandemic
What was tested
Treatment tested
- Walking
What it measured
Main measures
Change in 6-minute Walk Test distance
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
Walking and mobility
Other measures (6)
Change in 12-item Multiple Sclerosis Walking Scale score
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
Walking and mobilityChange in Fatigue Severity Scale score
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
FatigueChange in Step Length
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
Change in Step Time
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
Change in Stride Velocity
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
Change in Cadence
Baseline, 6 weeks (after intervention), and 12 weeks (6-week follow-up)
Who could take part
MS (type not specified) · 18 to 75
Show the full criteria
Inclusion criteria
* Self-identified difficulty walking * Definitive diagnosis of multiple sclerosis from a neurologist * Signed an approved consent form * Ability to ambulate for unaided for 6-minutes continuously with or without an assistive device (e.g. a cane or brace) * Has not had a multiple sclerosis relapse in the past 6 weeks
Exclusion criteria
* Unwilling or unable to complete assessments * Unwilling or able to complete assessments and or intervention without the use of portable functional electrical stimulation devices * Medical history of concomitant condition unrelated to multiple sclerosis which may impact results including: other neurological conditions including stroke, Parkinson's disease, or orthopedic, or cardiopulmonary conditions that affect walking * Had a major change in exercise habits in the past three months * Individuals reporting change in any disease modifying treatment or steroid use during the past 6 weeks * Unable to walk for 6 minutes continuously without physical assistance * Medical history of unstable angina, uncontrolled cardiac dysrhythmias causing symptoms, symptomatic severe aortic stenosis, uncontrolled symptomatic heart failure, acute pulmonary embolus or pulmonary infarction, history of deep vein thrombosis, acute myocarditis or pericarditis, acute systemic infection, uncontrolled hypertension, and uncontrolled diabetes * Has an abnormal response to exercise * Cannot adhere to protocol * Determined to be unsafe at the discretion of the research team including individuals unwilling to wear safety "gait belt" during testing or not willing to wear proper footwear.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study will compare the effectiveness of a traditional, continuous walking rehabilitation program for people with MS to the novel intervention of an intermittent or interval walking rehabilitation program. Half of the participants will receive the continuous walking program while the other half will receive the novel intermittent walking program.
Loading reviews and guidelines…
History
Started
Jul 2019
Main results due
Feb 2023
Finished
Feb 2023