Individualized Physiotherapy and Activity Coaching for Multiple Sclero
Individualized Physiotherapy and Activity Coaching for Multiple Sclerosis (IPAC-MS): A Randomised Controlled Trial
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Individualized behavioural physical activity intervention
What it measured
Main measures
Godin Leisure Time Exercise Questionnaire (GLTEQ) Score
baseline to 12 months
Physical function
Other measures (4)
Multiple Sclerosis Impact Scale version 2 (MSIS-29 v2)
baseline to 12 months
Quality of life (reported by participants)Multiple Sclerosis Self Efficacy Scale (MSSE)
baseline to 12 months
Quality of life (reported by participants)Interviews and Exit surveys
after intervention (at 12 month point for intervention group and 18 month for wait-list control) group
Intervention Description
after intervention (at 12 month point for intervention group and 18 month for wait-list control group)
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* clinically definite MS (diagnosed by a neurologist) * patient determined disease steps (PDDS) less than or equal to 6 (i.e. not wheel-chair bound) * GLTEQ\<24 (not active enough for health benefits)
Exclusion criteria
* medical instability (PAR-Q moderate-high risk of exercise-related harm) * persons unable to provide consent * persons under the age of 18 years old
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Multiple Sclerosis (MS) is a chronic neurological disease that places a high burden on patients, families and society. Physical activity in MS is associated with improved fitness, symptoms, and function, fewer relapses, and fewer brain lesions on MRI. Saskatchewan has one of the highest rates of MS worldwide, and a recent survey estimated approximately 80% of persons living with MS are not sufficiently active for health benefits. Individuals living with MS recognize the importance of physical activity, but often indicate a lack support, including limited access to professionals knowledgeable about both MS and physical activity. There is a need to identify effective interventions for improving activity levels safely and appropriately. Behaviour change strategies target specific behaviours involved in increasing and maintaining physical activity. The primary objective of this project is to determine if individualized behaviour change strategies delivered by neurophysiotherapists increases physical activity in MS. Participants will be randomly assigned into two groups. The intervention group will receive individualized behaviour change strategies delivered through the support of neurophysiotherapists for 12 months. The wait-list control group will receive usual care for 12 months, and then be offered the intervention for a 6-month period at the end of the study period. The long-term goal of this research is to help decrease the burden of MS by identifying new opportunities for increasing physical activity.
Papers
Results
Individualised behaviour change strategies for physical activity in multiple sclerosis (IPAC-MS): protocol for a randomised controlled trial.Trials · 2019
Results
Donkers SJ, Evans C, Levin MC, Ives K, Le H, Lim HJ, Knox KB. Individualized Physiotherapy and Activity Coaching in Multiple Sclerosis (IPAC-MS): Results of a Randomized Controlled Trial. Arch Phys Med Rehabil. 2025 Aug;106(8):1145-1154. doi: 10.1016/j.apmr.2025.02.005. Epub 2025 Feb 15.
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History
Started
Jul 2019
Main results due
Jan 2021
Finished
Jun 2021