TRAIN-BW: Backward Walking Training in Multiple Sclerosis
TRAIN-BW: Backward Walking Training in Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Backward Walking Training
Compared with
- Forward Walking Training
What it measured
Main measures
Sway during quiet stance
Change in sway at 8 weeks
Stepping latency on push-and-release test
Change in stepping latency at 8 weeks
Myelin repair
Other measures (6)
Client Satisfaction Questionnaire (CSQ-8)
8 weeks
Quality of life (reported by participants)Patient Global Impression of Change
8 weeks
Number of Active Minutes
Change in Physical Activity measures at 8 weeks
Number of Falls
6 months
Walking and mobilityForward and Backward Velocity and Double Support Time
Change in velocity and double support time at 8 weeks
Walking and mobilityABC Scale
Change in balance confidence at 8 weeks
Walking and mobility
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* Diagnosis of MS * PDDS \<6, indicating ability to ambulate with or without an assistive device >/= 50% of the time * Self-reported walking dysfunction as evidenced by a score of >/= 30 on MSWS-12 OR reports of 2 or more falls in the prior 6 months, indicating a frequent faller.
Exclusion criteria
* MS relapse within the past 30 days * comorbid neurological disorder * acute orthopedic disorder/injury * unable to follow study-related commands
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Individuals with multiple sclerosis (MS) experience in impairments in mobility and cognition that increase the risk for accidental falls. More than 50% of individuals with MS experience injurious falls within a 6-month period. Current interventions to improve fall risk have focused on forward walking (FW) and balance training, resulting in small declines in the relative risk for falls with a large degree of variability. Interestingly, motor differences between MS and healthy controls are more pronounced in backward walking (BW), yet no studies have investigated BW training as an intervention to reduce fall risk in persons with MS. This study will investigate the feasibility, acceptability and impact of BW training compared to forward walking training on motor function and fall risk in persons with MS.
Papers
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History
Started
Jan 2020
Main results due
May 2026
Finished
May 2026