The Effect of Local Vibration Applied to Spastic Gastrocnemius on Muscle Architecture and Functional Properties in Multiple Sclerosis Patients

Status unknownNot a drug-phase studyMS (type not specified)NCT04192786

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Standard physiotherapy program+50 Hz local vibration
  • Standard physiotherapy program+100 Hz local vibration

Compared with

  • Standard physiotherapy program

What it measured

Main measures

  • Evaluation of Muscle Thickness and Fascicle Length with Ultrasonography

    3 minutes

  • Evaluation of Pennation Angle with Ultrasonography

    2 minutes

Other measures (6)

  • Assessment of spasticity

    5 minutes

    Spasticity
  • Assessment of viscoelastic properties of muscle

    5 minutes

  • Assessment of ankle proprioception

    5 minutes

    Physical function
  • Assessment of single leg balance

    3 minutes

    Walking and mobility
  • Assessment of balance

    10 minutes

    Walking and mobility
  • Assessment of gait characterictics

    5 minutes

    Walking and mobility

Who could take part

MS (type not specified) · 18 to 65

Show the full criteria

Inclusion criteria

* > 18 years * EDSS\<5,5 * Gastrocnemius spasticity\<2

Exclusion criteria

* having any injury or surgery of the lower extremity * having systemic and metabolic disease * having behavioral and cognitive problems that prevent consistence to guidelines given

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Gastrocnemius spasticity is one of the main complaints in Multiple Sclerosis patients.Local muscle vibration is a method used for spasticity inhibition. However, when the studies in the literature are examined; It is noted that local vibration applications for spasticity are usually single sessions and evaluate the acute effect, do not produce functional outputs, there is no consensus on frequency and amplitude and the changes in muscle architecture are not examined. In this study, we aimed to investigate the effect of local vibration applied on spastic gastrocnemius on muscle architectural and functional properties in Multiple Sclerosis patients in addition to the standard physiotherapy program. The study was planned to include 3 groups, 2 treatment and 1 control group. The control group will receive standard physiotherapy, one of the treatment groups will receive 50 Hz local vibration in addition to standard physiotherapy, and other treatment group will receive 100 Hz local vibration in addition to standard physiotherapy. Disease severity, gastrocnemius spasticity, architectural and viscoelastic properties of muscle, ankle proprioception, balance and gait skills will be evaluated before and after 8 weeks treatment program. As a result; effectiveness of local vibration in addition to standard physiotherapy program and whether there is a difference between applications at different frequencies will be examined.

Papers

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History

    1. Started

      Dec 2019

    2. Main results due

      Nov 2020

    3. Finished

      Dec 2020

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