Motivation, Neuropsychological Testing and Functional Exercise in Virtual Environment for Persons With Multiple Sclerosis or Parkinson's Disease

CompletedNot a drug-phase studyMS (type not specified)NCT04266444

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Exergaming in virtual environment

What it measured

Main measures

  • Change in Box & Blocks Test from baseline

    Assessment at baseline and after two weeks

    Arm and hand function
  • Change in Frontal Assessment Battery (FAB) score from baseline

    Assessment at baseline and after two weeks

  • Intrinsic Motivation Inventory (IMI) scores

    Assessment at the end of each exergaming session; median across assessments will be taken as the outcome on each subscale

Other measures (2)

  • Change in Delis-Kaplan Executive Function System (D-KEFS) scores from baseline

    Assessment at baseline and after two weeks

  • Change in Judgment of Line Orientation (JLO)

    Assessment at baseline and after two weeks

Who could take part

MS (type not specified) · 18 and over

Show the full criteria

Inclusion criteria

* diagnose of Parkinson's disease or multiple sclerosis; * Mini Mental State Examination score above 24; * preserved upper limb function; * for Parkinson's disease patients Hoehn and Yahr scale score between 2 and 3.

Exclusion criteria

* any communicable disease; * severe vision impairment.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The aim of the study is to optimise the hand dexterity exercising program in virtual reality (VR) for patients with multiple sclerosis and Parkinson's disease. Little research has been published on this topic, but the preliminary results are promising. Different levels of difficulty of a VR game will be tested. The patients will be assessed using neuropsychological tests of executive functions, visuospatial abilities, mental speed, flexibility and motor speed. Functional ability, coordination and cognitive abilities will also be assessed.

Papers

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History

    1. Started

      Feb 2020

    2. Main results due

      Sept 2021

    3. Finished

      Sept 2021

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