Effects of Ten-Weeks Resistance Training on Neuromuscular Performance, Heart Rate Variability, Sleep Quality and Mobility in Persons With Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT04276324

What it found

No results found

We found no results in the registry or in papers.

This trial finished 6 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Resistance training

Given to everyone in the trial

  • Testing sessions

What it measured

Main measures

  • Maximal Voluntary Isometric Contraction of Knee Extension

    Before the program training

  • Maximal Voluntary Isometric Contraction of Knee Extension

    After 10 weeks

  • Rate of Force Development

    Before the program training

  • Rate of Force Development

    After 10 weeks

  • Central Activation Ratio

    Before the program training

  • Central Activation Ratio

    After 10 weeks

  • Spasticity

    Before the program training

    Spasticity
  • Spasticity

    After 10 weeks

    Spasticity

Other measures (10)

  • Walking speed

    Before the program training

    Walking and mobility
  • Walking speed

    After 10 weeks

    Walking and mobility
  • Static balance

    Before the program training

    Walking and mobility
  • Static balance

    After 10 weeks

    Walking and mobility
  • Functional capacity

    Before the program training

  • Functional capacity

    After 10 weeks

  • Heart Rate Variability

    Before the program training

    Mood and sleep
  • Heart Rate Variability

    After 10 weeks

    Mood and sleep
  • Sleep Quality

    Before the program training

    Mood and sleep
  • Sleep Quality

    After 10 weeks

    Mood and sleep

Who could take part

MS (type not specified) · 20 to 60

Show the full criteria

Inclusion criteria

* mild or moderate disability with clinical mild spastic-ataxic gait disorder. * stable phase of the disease.

Exclusion criteria

* Expanded Disability Status Scale (EDSS) \< 6. * relapsing disease within the preceding 12 months. * corticosteroid treatment within the last months before study inclusion.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Multiple Sclerosis (ME) is a degenerative, inflammatory and autoimmune demyelinating disease of the central nervous system, characterized by demyelination due to inflammation and degeneration of the myelin sheaths enveloping nerves of the eye, periventricular grey matter, brain, spinal cord and brainstem. The symptoms associated with MS include symptomatic fatigue, muscle weakness, ataxia, mobility and balance problems or cognitive problems. Strength training has been shown to improve strength and mobility in persons with MS.

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History

    1. Started

      Mar 2020

    2. Main results due

      Jun 2020

    3. Finished

      Oct 2020

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