Acute Intermittent Hypoxia in Persons With Multiple Sclerosis
Evaluating the Use of Acute Intermittent Hypoxia to Improve Symptoms in Persons With Multiple Sclerosis
What it found
We found no results in the registry or in papers.
This trial finished 7 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Intermittent Hypoxia
Placebo
- Sham Hypoxia
What it measured
Main measures
Voluntary Ankle Strength
60 minutes post-intervention
Physical function
Other measures (2)
Electromyogram activity
60 minutes post-intervention
Symbol Digit Modalities Test
60 minutes post-intervention
Thinking and memory
Who could take part
Relapsing MS · 18 to 75
Show the full criteria
Inclusion criteria
* Have relapsing-remitting MS * Volitional ankle plantar flexion strength in at least one leg * Are relapse free for 30 days * Patient-Determined Disease Steps scale score between 3 and 5 (3=gait disability to 5=late cane, need cane to walk 25 feet)
Exclusion criteria
* Currently taking antispasticity medications, * Have cardiovascular or respiratory/pulmonary disorders, metabolic dysfunction, or prior diagnoses of obstructive sleep apnea * Pregnant or nursing women (safety for developing fetus or infant is unknown) * Cognitive concerns (must be able to consent to study, follow steps)
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The overall objective of this project is to investigate the effectiveness of Acute Intermittent Hypoxia (AIH), to improve muscle strength and activity level in individuals with relapsing-remitting MS.
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History
Started
Jun 2018
Main results due
Oct 2019
Finished
Dec 2019