Brain Activity Changes Following Neuroproprioceptive Physiotherapy in

Brain Activity Changes Following Neuroproprioceptive Physiotherapy in Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT04448444

What it found

No results found

We found no results in the registry or in papers.

This trial finished 9 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Motor Program Activating Therapy
  • Vojta reflex locomotion

What it measured

Main measures

  • Brain activity

    0 month

    MRI lesionsNerve conduction tests

  • Brain activity

    0 and 2 months

    MRI lesionsNerve conduction tests

Other measures (5)

  • Nine Hole Peg Test - NHPT

    2 months

    Arm and hand function

  • Paced Auditory Serial Addition Test - PASAT

    2 months

    Thinking and memory

  • Berg Balance Scale - BBS

    2 months

    Walking and mobility

  • Timed 25 Foot Walk - T25FW

    2 months

    Disability progressionWalking and mobility

  • Timed Up and Go - TUG

    2 months

    Walking and mobility

Who could take part

MS (type not specified) · 18 to 70

Show the full criteria

Inclusion criteria

* definite MS * stable clinical status in the preceding 3 months * imuno-modulatory treatment for at least two years (including glatiramer acetate, interferon beta-1a, 1b, mitoxantrone, fingolimod, natulizumab) * Expanded Disability Status Scale (EDSS)≤6 * predominant motor impartment * six months or more without any physiotherapy * ability to undergo ambulatory physiotherapy Exlusion criteria: -other neurological disease or conditions disabling movement

Exclusion criteria

Not separately supplied in the registry.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Imaging methods bring new possibilities for describing the brain plasticity processes that underly the improvement of clinical function after physiotherapy in people with multiple sclerosis (pwMS). The study determined whether facilitation physiotherapy could enhance brain plasticity, compared two facilitation methods, and looked for any relation to clinical improvement in pwMS.

Papers

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    History

      1. Started

        May 2015

      2. Main results due

        May 2017

      3. Finished

        Nov 2019

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