Effects of Ten-Weeks Progressive Resistance Training on Neuromuscular
Effects of Ten-Weeks Progressive Resistance Training on Neuromuscular Performance, Mobility, Heart Rate Variability and Sleep Quality in Persons With Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Physical exercise
Given to everyone in the trial
- Testing sessions
What it measured
Main measures
Maximal Voluntary Isometric Contraction of Knee Extension
Before the program training
Physical functionMaximal Voluntary Isometric Contraction of Knee Extension
After 10 weeks
Physical functionRate of Force Development
Before the program training
Rate of Force Development
After 10 weeks
Central Activation Ratio
Before the program training
Central Activation Ratio
After 10 weeks
Spasticity
Before the program training
SpasticitySpasticity
After 10 weeks
Spasticity
Other measures (10)
Walking speed
Before the program training
Walking and mobilityWalking speed
After 10 weeks
Walking and mobilityStatic Balance
Before the program training
Walking and mobilityStatic Balance
After 10 weeks
Walking and mobilityFunctional capacity
Before the program training
Functional capacity
After 10 weeks
Heart Rate Variability
Before the program training
Mood and sleepHeart Rate Variability
After 10 weeks
Mood and sleepSleep Quality
Before the program training
Mood and sleepSleep Quality
After 10 weeks
Mood and sleep
Who could take part
MS (type not specified) · 20 to 65
Show the full criteria
Inclusion criteria
* mild or moderate disability with clinical mild spastic-ataxic gait disorder. * stable phase of the disease.
Exclusion criteria
* Expanded Disability Status Scale (EDSS) \< 6. * relapsing disease within the preceding 12 months. * corticosteroid treatment within the last months before study inclusion.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Multiple Sclerosis (ME) is a degenerative, inflammatory and autoimmune demyelinating disease of the central nervous system, characterized by demyelination due to inflammation and degeneration of the myelin sheaths enveloping nerves of the eye, periventricular grey matter, brain, spinal cord and brainstem. The symptoms associated with MS include symptomatic fatigue, muscle weakness, ataxia, mobility and balance problems or cognitive problems. Strength training has been shown to improve strength and mobility in persons with MS.
Papers
Results
Effects of fast-velocity concentric resistance training in people with multiple sclerosis: A randomized controlled trial.Acta Neurol Scand · 2022
Results
Andreu-Caravaca L, Ramos-Campo DJ, Chung LH, Rubio-Arias JA. Can strength training modify voluntary activation, contractile properties and spasticity in Multiple Sclerosis?: A randomized controlled trial. Physiol Behav. 2022 Oct 15;255:113932. doi: 10.1016/j.physbeh.2022.113932. Epub 2022 Jul 27.Results
Andreu-Caravaca L, Ramos-Campo DJ, Abellan-Aynes O, Avila-Gandia V, Chung LH, Manonelles P, Rubio-Arias JA. 10-Weeks of resistance training improves sleep quality and cardiac autonomic control in persons with multiple sclerosis. Disabil Rehabil. 2022 Sep;44(18):5241-5249. doi: 10.1080/09638288.2021.1934738. Epub 2021 Jun 9.
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History
Started
Jul 2020
Main results due
Oct 2020
Finished
Oct 2020