Efficacy of PoNS in Reducing Symptoms of Multiple Sclerosis
Examining the Efficacy of Non-invasive Neuromodulation in Reducing Symptoms of Multiple Sclerosis - a Pilot Study
What it found
We found no results in the registry or in papers.
This trial finished 10 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Portable Neuromodulation Stimulator
What it measured
Main measures
Dynamic Gait Index
14 weeks
Walking and mobilityHow the body handles the medicine
Who could take part
Progressive MS · 28 to 62 · EDSS 3.0 to 6.0
Show the full criteria
Inclusion criteria
* Relapsing/remitting or secondary progressive MS with balance and gait problems; * Recent EDSS score of 3.0 - 6.0; * Provided informed consent and willing to participate
Exclusion criteria
* Use of tobacco products; * Oral health problems including abrasions, cuts, cold sores, piercings, or tissue inflammation in the oral cavity; * Baseline EDSS >6.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The purpose of this pilot study is to determine whether a program involving both in-lab and at-home training using cranial nerve stimulation (CN-NINM) delivered via the tongue can reduce symptoms of multiple sclerosis (MS) and improve movement control and therefore provide ground work for a controlled clinical trial. The effects of the stimulation will be measured using a variety of standardized tests of movement control and cognitive function, functional brain imaging, and MS-specific surveys of your quality of life.
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History
Started
Dec 2014
Main results due
Aug 2016
Finished
Aug 2016