Conventional Vestibular Training Versus Immersive Virtual Reality- Bas
Feasibility and Safety of an Immersive Virtual Reality-based Vestibular Rehabilitation Program for Dizziness, Balance and Fatigue Improvement in People With Multiple Sclerosis: Protocol for a Pilot Randomised Controlled Study
What it found
The trial ended early for another reason (see below).
Reason given: Lack of funding.
What was tested
Treatment tested
- Immersive Virtual-based vestibular rehabilitation
Compared with
- Conventional vestibular rehabilitation protocol
What it measured
Main measures
Feasibility of virtual reality-based vestibular rehabilitation
7 weeks of intervention
Quality of life (reported by participants)FeasibilitySafety of virtual reality-based vestibular rehabilitation
7 weeks of intervention
Walking and mobilitySafety
Other measures (4)
Change from baseline dizziness symptoms at 7 weeks
7 weeks after intervention
Change from baseline static balance at 7 weeks
7 weeks after intervention
Walking and mobilityChange from baseline fatigue at 7 weeks
7 weeks after intervention
FatigueChange from baseline quality of life at 7 weeks
7 weeks after intervention
Quality of life (reported by participants)
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* Both male and female subjects from 18-65 years old * Clinically diagnosed with any type of multiple sclerosis in accordance with the revised McDonald criteria * With walking ability according to the Expanded Disability Status Scale score (EDSS =6) * With the objective presence of dizziness symptoms (Dizziness Handicap Inventory = 16)
Exclusion criteria
* Blurred vision * Cognitive impairment (Mini Mental State Examination =24) * Another neurologic disorder contributing to balance impairment * Relapse within the last 3 months * Changes in pharmacotherapy within the last 3 months * History of vestibular rehabilitation within the last 6 months * Acute cardiovascular of respiratory illness * Any other contraindication to physical activity
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The effectiveness of convectional vestibular training for balance and dizziness rehabilitation in people with multiple sclerosis has been recently demonstrated in a meta-analysis by this research team (doi: 10.3390/jcm9020590). Furthermore, non-immersive virtual reality-based environments seem to be useful for balance and gait rehabilitation in this population (doi: 10.1177/0269215518768084). However, nothing is known about the feasibility and effectiveness of immersive virtual reality-based rehabilitation in people with multiple sclerosis. The primary aim of this research is to determine the feasibility, safety and effectiveness of an immersive virtual reality-based vestibular training for dizziness, balance and fatigue rehabilitation, compared to conventional vestibular training.
Papers
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History
Started
Jan 2026
Main results due
Dec 2028
Finished
Dec 2029