Bright Light Therapy as Possible Treatment Option for MS-Fatigue
Bright Light Therapy as Possible Treatment Option for Fatigue in Multiple Sclerosis Patients - A Randomised Controlled Trial
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- bright light therapy
Placebo
- dim red light
What it measured
Main measures
Change in fatigue levels
Day 1, Day 14, Day 30, Day 46
FatigueChange in fatigue levels
Day 15, Day 31
Fatigue
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* MS patients who suffer from fatigue * Age between 18 and 65 years old * FSS Score of 36 or greater * ESS Score of 12 or greater * MEQ Score between 31 and 69 * BDI Score lower than 19 * BAI Score lower than 27 * EDSS lower than 4
Exclusion criteria
* sleep disorders (periodic limb movement disorders, obstructive or central sleep apnea, REM sleep behavior disorders) * change of antidepressive/fatigue influencing/sleep influencing/photosensizing/MS medication within the preceding 4 weeks * clinical MS-relapse within the preceding 4 weeks * consumption of alcohol: more than 1 glass per day * consumption of caffeine: more than 4 cups per day * current shift work * Jet lag (travelled across two or more time zones within 90 days before study screening * Retinopathy or other visual diseases/abnormalties * Traumatic brain injury within the preceding 5 years * pregnant or lactating * Participation in another clinical trial at the same time
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study aims to investigate the effect of a 2-week trial of bright light therapy (BLT, 10.000 lx) on fatigue in multiple sclerosis (MS) patients. In this randomised placebo-controlled trial, the effect of bright light therapy will be compared to dim red light. MS-fatigue is quantified by patients using a visual analogue scale (VAS) and activity levels, subjective and objective sleep parameters and daytime sleepiness are measured.
Papers
Loading reviews and guidelines…
History
Started
Dec 2019
Main results due
Sept 2021
Finished
Jan 2022