Virtual Reality in Physical Therapy in Multiple Sclerosis
Effect of Neuroproprioceptive "Facilitation, Inhibition" Physical Therapy Using Virtual Reality on Upper Limb Mobility and Postural Stability in Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Neuroproprioceptive "facilitation and inhibition" in virtual reality
Compared with
- Neuroproprioceptive "facilitation and inhibition"
What it measured
Main measures
Nine Hole Peg Test (9HPT) - change pre/post intervention
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Disability progressionBox and Block Test (BNB) - change pre/post intervention
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Arm and hand functionHand Grip Strength (HGS) -change pre/post intervention
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Arm and hand functionPhysical functionTremor; Frequency for which the smoothed power spectral density is maximal (fMAX)
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Physical functionTremor; Power of the signal in band from f1 to f2 (Pf1-f2)
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Physical functionFive times Sit to Stand test (5STS) -change pre/post intervention
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Other measures (2)
Multiple Sclerosis Impact Scale (MSIS-29) - change pre/post intervention
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Quality of life (reported by participants)EQ-5D-3L-health questionnaire - change pre/post intervention
Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Walking and mobilityPainMood and sleepQuality of life (reported by participants)
Who could take part
MS (type not specified) · 18 to 75
Show the full criteria
Inclusion criteria
* The inclusion criteria comprise of a definite diagnosis of multiple sclerosis, EDSS score ≥ 2 a ≤ 7 ((10); determined by neurologist), no history of relapse, no history of change in disease-modifying treatment, no history of corticosteroid therapy in the past three months prior to recruitment.
Exclusion criteria
* The exclusion criteria include other factors influencing mobility (history of stroke, pregnancy, traumatic injury of limb/s. Severe cardiovascular or orthopedic dysfunction, impaired cognitive functions in the course of examination and/or consecutive therapy.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS). The conceptual idea is to compare two kinds of neuroproprioceptive "facilitation and inhibition" physical therapy, first in a real environment and second in virtual reality, in out-patient therapy that will be held in 15 hourly therapies, 2x a week in a period of two months. The efficacy will be assessed by a blinded independent clinical examiner using clinical examination and questionnaire survey before and in a week following the therapeutic intervention. The main focus is on upper limb gross and fine motor skills, trunk stability and stability, and sit to stand stability.
Papers
Loading reviews and guidelines…
History
Started
Apr 2021
Main results due
Jan 2025
Finished
Feb 2025