Impact of Neuropsychological Disorders on Visual Exploration, Walking Initiation and Walking in Multiple Sclerosis

CompletedNot a drug-phase studyRelapsing MSNCT04837365

What it found

No results found

We found no results in the registry or in papers.

What was tested

Treatment tested

  • Three dimensional gait analysis with eyetracking

What it measured

Main measures

  • Cadence of walking (in cycles.min-1)

    60 days

    Walking and mobility
  • Step length (in m)

    60 days

    Walking and mobility
  • Walking speed (in m.s-1)

    60 days

    Walking and mobility
  • Range of motion in the lower limbs in degrees

    60 days

    Walking and mobility

Other measures (5)

  • Ocular fixation time (measured in ms)

    60 days

    Thinking and memoryWalking and mobility
  • Muscle contractions determined by the electromyogram (EMG) (mV)

    60 days

    Walking and mobility
  • Displacements (in mm) during walking

    60 days

    Walking and mobility
  • Acceleration (in mm.s-2) during walking

    60 days

    Walking and mobility
  • Joint angles

    60 days

    Walking and mobility

Who could take part

Relapsing MS · 18 to 55

Show the full criteria

Inclusion criteria

* Understanding and able to speak French * Carriers of MS with relapsing remitting form (RRMS-RR) with an EDSS \<4 * No significant motor, cerebellar or somesthesia disorders of the upper limbs or visual disturbances (side to a visual EDSS \<2) * Absence of corticosteroid intake in the last four weeks * Benefiting from health insurance coverage * Not showing any flare-ups or worsening of the disease in the last 6 weeks * No botulinum toxin injection for more than 4 months

Exclusion criteria

* People with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general ailments, perceptual or dysarthric disorders preventing verbal communication or reading, * Treatment with psychotropic drugs (except benzodiazepines and hypnotics). * Refusal to participate after clear and fair information about the study. * Adults under tutorship, curatorship or safeguard of justice * With orthopedic treatment influencing walking * Pregnant woman

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The study involves MS patients with and without neuropsychological disorders. The patient will benefit from: * A routine neuropsychological assessment, including a cognitive and emotional assessment * A clinical examination * A three-dimensional analysis of movement

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History

    1. Started

      May 2021

    2. Main results due

      Nov 2025

    3. Finished

      Dec 2025

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