Sonification Techniques for Gait Training
Sonification Techniques for Gait Training: a Pilot Multicentric Randomized Controlled Trial
What it found
No result yet.
What was tested
Treatment tested
- Gait rehabilitation with "sonification"
Compared with
- Standard gait rehabilitation (without sonification)
What it measured
Main measures
Change in the Six Minutes Walking Test
Change from Baseline Six Minutes Walking Test at 7 weeks
Walking and mobility
Other measures (3)
Mini BesTest
Up to 11 weeks
Walking and mobilityDynamic Gait Index
Up to 11 weeks
Walking and mobilityTimed Up & Go
Up to 11 weeks
Walking and mobility
Who could take part
MS (type not specified) · Up to 80
Show the full criteria
Inclusion criteria
Inclusion criteria (stroke patients) * Age \< 80 * Mini Mental State Examination > 24 * Modified Rankin Scale: 1-3 * Single hemisphere lesion * Stabilized disease (> 6 months after the acute event) * Impairment in gait parameters (e.g. velocity, perceived fatigue etc) * Motor independence during walking (without orthotic devices and aids) but with pathological pattern (spasticity level: Ashworth \< 2) Inclusion criteria (patients with Parkinson's disease) * Age \< 80 * Mini Mental State Examination > 24 * Unified Parkinson Disease Rating Scale score (Parte III): \< 28 * Stabilized disease and drug therapy * Altered gait patterns * Motor independence during walking (without orthotic devices and aids) but with pathological pattern Inclusion criteria (patients with multiple sclerosis): * Age \< 60 * Mini Mental State Examination > 24 * Expanded Disability Status Scale score: 3-5 * Stabilized disease in the last 6 months (without relapse or disability progression) * Altered gait patterns (i.e., careening, slowing down, spasticity: Ashworth \< 2, etc.) * Motor independence during walking Exclusion Criteria (stroke patients) * Multiple or bilateral lesions * Neglect * Equinism * Spasticity: Ashworth >2 * Structured (non-elastic) Achilles tendon retraction * Neurotoxin in the 3 months prior to the study * Baclofen introduced or modified in the week before the start of the study * Previous or concurrent diseases disabling the lower limb functions * Rehabilitative treatments with music in the year before the study Exclusion criteria (patients with Parkinson's disease): * Previous or concurrent diseases disabling the lower limb functions * Changes of drug therapy during the study * Rehabilitative treatments with music in the year before the study Exclusion criteria (patients with multiple sclerosis): * Previous or concurrent diseases disabling the lower limb functions * Neurotoxin in the 3 months prior to the study * Baclofen introduced or modified in the week before the start of the study * Spasticity: Ashworth >2 * Structured (non-elastic) Achilles tendon retraction * Rehabilitative treatments with music in the year before the study
Exclusion criteria
Not separately supplied in the registry.
As registered. Criteria can change, so ask the trial team or your neurologist.
Contact details on the registryAbout this trial
In the sponsor's words
Music therapy is widely used in relational and rehabilitation settings. In addition to Neurologic Music Therapy and other music-based techniques, "sonification" approaches were recently introduced in the field of rehabilitation. The "sonification" can be defined as a properly selected set of sonorous-music stimuli are associated with patient movements mapping. In fact, the auditory-motor feedback can replace damaged proprioceptive circuits with a consequent improvement of the rehabilitation process. Interventions with "sonification" facilitate sensorimotor learning, proprioception and movements planning and execution improving global motor parameters. This study proposes the use of musical auditory cues which includes the melodic-harmonic component of the music. This kind of sonification makes the feedback pleasant and predictable as well as potentially effective. The investigators propose to apply and assess the effectiveness of this kind of sonification on gait training and other secondary outcomes in stroke, Parkinson's disease and multiple sclerosis population. Also, the investigators will assess the impact of "sonification" on the level of fatigue perceived during the rehabilitation process and on the quality of life. The study is a multicenter randomized controlled trial and will involve 120 patients that will undergo standard motor rehabilitation or the same rehabilitation but with the sonification support. The interventions will be evaluated at the baseline, after 10 sessions, after 20 sessions and at follow-up (one month after the end of the treatment). The assessment will include functional, motor, fatigue and quality of life evaluations. The collected data will be statistically processed.
Papers
Background
Altenmuller E, Marco-Pallares J, Munte TF, Schneider S. Neural reorganization underlies improvement in stroke-induced motor dysfunction by music-supported therapy. Ann N Y Acad Sci. 2009 Jul;1169:395-405. doi: 10.1111/j.1749-6632.2009.04580.x.Background
Ashoori A, Eagleman DM, Jankovic J. Effects of Auditory Rhythm and Music on Gait Disturbances in Parkinson's Disease. Front Neurol. 2015 Nov 11;6:234. doi: 10.3389/fneur.2015.00234. eCollection 2015.Background
Bangert M, Altenmuller EO. Mapping perception to action in piano practice: a longitudinal DC-EEG study. BMC Neurosci. 2003 Oct 15;4:26. doi: 10.1186/1471-2202-4-26.Background
Bangert M, Peschel T, Schlaug G, Rotte M, Drescher D, Hinrichs H, Heinze HJ, Altenmuller E. Shared networks for auditory and motor processing in professional pianists: evidence from fMRI conjunction. Neuroimage. 2006 Apr 15;30(3):917-26. doi: 10.1016/j.neuroimage.2005.10.044. Epub 2005 Dec 27.Background
Baram Y, Miller A. Auditory feedback control for improvement of gait in patients with Multiple Sclerosis. J Neurol Sci. 2007 Mar 15;254(1-2):90-4. doi: 10.1016/j.jns.2007.01.003. Epub 2007 Feb 20.Background
Baumann S, Koeneke S, Schmidt CF, Meyer M, Lutz K, Jancke L. A network for audio-motor coordination in skilled pianists and non-musicians. Brain Res. 2007 Aug 3;1161:65-78. doi: 10.1016/j.brainres.2007.05.045. Epub 2007 Jun 4.Background
Bella SD, Benoit CE, Farrugia N, Keller PE, Obrig H, Mainka S, Kotz SA. Gait improvement via rhythmic stimulation in Parkinson's disease is linked to rhythmic skills. Sci Rep. 2017 Feb 24;7:42005. doi: 10.1038/srep42005.Background
Bevilacqua F, Boyer EO, Francoise J, Houix O, Susini P, Roby-Brami A, Hanneton S. Sensori-Motor Learning with Movement Sonification: Perspectives from Recent Interdisciplinary Studies. Front Neurosci. 2016 Aug 25;10:385. doi: 10.3389/fnins.2016.00385. eCollection 2016.Background
Brodie MA, Dean RT, Beijer TR, Canning CG, Smith ST, Menant JC, Lord SR. Symmetry matched auditory cues improve gait steadiness in most people with Parkinson's disease but not in healthy older people. J Parkinsons Dis. 2015;5(1):105-16. doi: 10.3233/JPD-140430.Background
Cha Y, Kim Y, Hwang S, Chung Y. Intensive gait training with rhythmic auditory stimulation in individuals with chronic hemiparetic stroke: a pilot randomized controlled study. NeuroRehabilitation. 2014;35(4):681-8. doi: 10.3233/NRE-141182.
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History
Started
Jan 2021
Main results due
Dec 2026
Finished
Jun 2027