The Effect of Trunk Stabilization Training Combined With Aerobic Training on Neuromuscular Parameters and Functional Exercise Capacity in Patients With Multiple Sclerosis

CompletedNot a drug-phase studyRelapsing MSNCT05029700

What it found

No results found

We found no results in the registry or in papers.

This trial finished 5 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Combined exercise training

Given to everyone in the trial

  • Aerobic training

What it measured

Main measures

  • Static balance

    4 weeks

    Walking and mobility
  • Dynamic balance

    4 weeks

    Walking and mobility

Other measures (2)

  • Lower extremity muscle strength

    4 weeks

    Physical function
  • Lower extremity muscle endurance

    4 weeks

    Physical function

Who could take part

Relapsing MS · 18 to 65

Show the full criteria

Inclusion criteria

* To be diagnosed with relapsing-remitting multiple sclerosis disease by a specialist physician * Not having an MS attack in the last 3 months * Having a disability level between 1 and 5 according to the Expanded Disability Status Scale * Not being included in the physiotherapy and rehabilitation program in the last 3 months

Exclusion criteria

* Using corticosteroids in the past 4 weeks * Being pregnant * Spinal deformities, spinal disc herniation or other spinal pathologies, orthopedic problems related to hip, knee, ankle

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Balance requires many central nervous system controlled functions, and most or all of these functions can be affected by MS, so balance is very often impaired in patients with MS. Core stability is also decreased in patients with MS. Core stability is among the most important factors that ensure the balance and walking of the participants in different environments and conditions during functional activities. In addition to core muscle activity, lower extremity muscle strength and endurance decrease due to the influence of central nervous system and decrease in physical activity. Functional exercise capacity also decreases due to the influence of the central nervous system and the decrease in physical activity in patients with MS. Despite all these symptoms and the benefits of exercise training, unfortunately, most MS patients are physically inactive, which can initiate a cycle of deconditioning and worsening of symptoms. In the literature, the combined effects of aerobic training and resistance training have been examined, and it has been stated that combining these two trainings will increase the effectiveness on symptoms. In recent years, trunk stabilization training has started to be included in physiotherapy and rehabilitation programs as an alternative method in patients with MS, based on the knowledge that core stability is effective on many functions and symptoms, as well as aerobic and resistance training. Considering that combined training practices are more effective in reducing symptoms, the investigators think that aerobic training and trunk stabilization training may be more effective in reducing symptoms in patients with MS when applied in combination. In addition, when all these studies were examined, the subtypes of MS patients included in the studies were generally not specified. The effects of these trainings on balance, core stability lower extremity muscle strength and endurance, and functional exercise capacity have not been demonstrated in patients with relapsing remitting MS (RR-MS), the most common type of MS disease. Therefore, the aim of this study is to examine the effects of trunk stabilization training combined with aerobic training on balance, core stability, lower extremity muscle strength and endurance, and functional exercise capacity in patients with RR-MS.

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History

    1. Started

      Jun 2019

    2. Main results due

      Dec 2020

    3. Finished

      Feb 2021

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