The Effect of Different Electrical Stimulations on Pain, Functional Capacity and Quality of Life in Multiple Sclerosis Patients

CompletedNot a drug-phase studyMS (type not specified)NCT05110586

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Electrotherapy

What it measured

Main measures

  • The Visual Analog Scale (VAS)

    Change from Baseline at 4 weeks

    Pain
  • Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain questionnaire

    Change from Baseline at 4 weeks

    Pain

Other measures (2)

  • 2 min walk test

    Change from Baseline at 4 weeks

    Walking and mobility
  • Multiple Sclerosis International Quality of Life Questionnaire

    Change from Baseline at 4 weeks

    Quality of life (reported by participants)

Who could take part

MS (type not specified) · 18 to 65

Show the full criteria

Inclusion criteria

* Having been diagnosed with MS according to McDonald 2010 diagnostic criteria * 18-65 years old * Volunteering to participate in the study

Exclusion criteria

* Less than 18 years old, over 65 years old * Having a history of trauma in the last 1 year * Having alcohol and substance addiction * Having diabetes mellitus * Presence of other known neurological disease * Having a pregnancy

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Multiple Sclerosis (MS) is a chronic neurological disease with local inflammation, gliosis and demyelination in the central nervous system (CNS). It is characterized by demyelinating plaques in the brain and spinal cord. Many different symptoms can be seen in the CNS, depending on the affected areas. One of the most common symptoms in these patients is pain. Approximately 50% of patients complain of pain at some point in their lives, and pain is one of the initial symptoms in 20%. Pain may originate from the musculoskeletal system; It may also develop due to inflammation and upper motor neuron damage and may have a neuropathic character . In conclusion, pain in MS negatively affects the physical and emotional functions and quality of life of patients. In addition to pharmacological treatments, non-pharmacological interventions such as electrotherapy and exercise are present among the available treatments for pain in MS patients.

Papers

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History

    1. Started

      May 2022

    2. Main results due

      Aug 2022

    3. Finished

      Aug 2022

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