White Matter Hyperintensities in Migraine: A Multi-modal Imaging Project to Classify Disease Pathology

Running, not recruitingNot a drug-phase studyMS (type not specified)NCT05112289

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Brain Neuroimaging

What it measured

Main measures

  • WMH imaging disease parameters

    3 months

    MRI lesions

Who could take part

MS (type not specified) · 20 to 59

Show the full criteria

Inclusion criteria

Inclusion Criteria - Migraine (N=20): * Female only. * Ages 20-45 years. * Presence of WMH on MRI.

Exclusion criteria

* History of SVI and/or history of MS or other neurological disease other than migraine. * History of cancer or organ transplantation. * Contraindication to MRI. * Pregnancy. * History of abnormal brain MRI other than WMH. * Subjects not willing to comply with the study procedures will be removed from the study. Inclusion Criteria - SVI disease (n=10): * Female only * Ages > 60 years. * Presence of WMH on MRI. Exclusion Criteria: * History of migraine and/or history of MS or other neurological disease other than SVI. * History of cancer or organ transplantation. * History of abnormal brain MRI other than WMH. * Pregnancy. * History of abnormal brain MRI other than WMH. * Subjects not willing to comply with the study procedures will be removed from the study. Inclusion Criteria - MS (n=10): * Female only. * Ages 20-45. * Presence of WMH on MRI. Exclusion Criteria: * History of migraine and/or history of SVI or other neurological disease other than MS. * History of cancer or organ transplantation. * History of abnormal brain MRI other than WMH. * Pregnancy. * History of abnormal brain MRI other than WMH. * Subjects not willing to comply with the study procedures will be removed from the study.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The purpose of this research is to better understand brain white matter hyperintensities (WMH) in women with migraines

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History

    1. Started

      Aug 2021

    2. Main results due

      Sept 2028

    3. Finished

      Sept 2028

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