The Chronic Effects of Low-Load Blood Flow Restriction or Standard of Care Resistance Exercise on Muscle and Neuromuscular Function in Patients With Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT05177952

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Blood Flow Restriction

Compared with

  • Standard of Care

What it measured

Main measures

  • Change in Functional Outcomes- 10meter

    Day 2, Week 4 and 8, Day 28

    Walking and mobility
  • Change in Functional Outcomes- 6min walk

    Day 2, Week 4 and 8, Day 28

    Walking and mobility
  • Change in Functional Outcomes- CST

    Day 2, Week 4 and 8, Day 28

  • Change in Functional Outcomes- 30CST

    Day 2, Week 4 and 8, Day 28

  • Change in Functional Outcomes- MFIS

    Day 2, Week 4 and 8, Day 28

    Fatigue

Other measures (1)

  • Changes in Strength

    Day 3, Week 4 and 8, Day 29

    Physical function

Who could take part

MS (type not specified) · 18 to 55

Show the full criteria

Inclusion criteria

* Females between the ages of 18 to 55 * Diagnosed with Multiple Sclerosis * Expanded Disability Status Score of 0 to 6.5 * Able to walk 10 meters without assistance * Are willing to come in for all 29 testing visits over 14 weeks

Exclusion criteria

* No other known cardiovascular, pulmonary, metabolic, muscular, and/or coronary heart disease * Multiple Sclerosis relapse in the past 30 days * Are not currently undergoing a rehabilitation protocol * Are not currently seeking medical care for a chronic condition that could limit exercise capacity other than multiple sclerosis * Are not currently pregnant

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

This research is being done to compare the current standard of care for strength training for patients with Multiple Sclerosis to lightweight resistance training with blood flow restriction.

Papers

Loading reviews and guidelines…

History

    1. Started

      Jan 2022

    2. Main results due

      Jan 2024

    3. Finished

      May 2024

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