Effectiveness of Cryotherapy on the Fatigue of Patients With Multiple
Effectiveness of Partial-body Cryotherapy on the Fatigue of Patients With Multiple Sclerosis During Readaptation Stay
We could not find results for this trial
What it found
We found no results in the registry or in papers.
This trial finished 2 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- partial-body cryotherapy chamber session
What it measured
Main measures
Fatigue syndrome
change from baseline (T0) to discharge between 3 to 5 weeks (T1), and 1 month (T2), 3 months (T3) and 1 year (T4) after hospitalization
Fatigue
Other measures (9)
spasticity symptom
change from baseline (T0) to discharge between 3 to 5 weeks (T1), and 1 year (T4) after hospitalization
Spasticityquality of Life evaluation
change from baseline (T0) to discharge between 3 to 5 weeks(T1), and 1 month (T2), 3 months (T3) and 1 year (T4) after hospitalization
Quality of life (reported by participants)pain evaluation
change from baseline (T0) to discharge between 3 to 5 weeks(T1), and 1 month (T2), 3 months (T3) and 1 year (T4) after hospitalization
Painquality of sleep
change from baseline (T0) to discharge between 3 to 5 weeks(T1), after 1 month (T2), 3 months (T3) and 1 year (T4)
Mood and sleepdepression symptoms
change from baseline (T0) to discharge between 3 to 5 weeks(T1), and 1 month (T2), 3 months (T3) and 1 year (T4) after hospitalization
Mood and sleepphysician's global assessment-physical endurance
change from baseline (T0) to discharge between 3 to 5 weeks (T1), and 1 year (T4) after hospitalization
Walking and mobilityhabit changes after rehabilitation stay
change from baseline (T0) to 1 month (T2), 3 months (T3) and 1 year (T4) after hospitalization
physician's global assessment-dynamic balance test
change from baseline (T0) to discharge between 3 to 5 weeks (T1), and 1 year (T4) after hospitalization
Walking and mobilityphysician's global assessement-static balance test
change from baseline (T0) to discharge between 3 to 5 weeks (T1), and 1 year (T4) after hospitalization
Walking and mobility
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* men and woen over 18 years old and under 65 years old * with multiple sclerosis * 0-6 points in the expanded disability states scale (EDSS) * with MS in remission (at least 6 months since the last relapse) * able to understand and respect the protocol and its requirement * who signed the consent prior to any other procedure protocol
Exclusion criteria
* major patients under guardianship/curators/legal protection * pregnant patients * patients with contraindication for cryotherapy * patients unable to complete the entire program * patients with substantial change in pharmacological treatment the month before the start of the study
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
the aim of the study is to evaluate the effectiveness of partial-body cryotherapy (PBC) on the symptoms of patients with multiple sclerosis during a rehabilitation stay.
Papers
Background
Pawik M, Kowalska J, Rymaszewska J. The effectiveness of whole-body cryotherapy and physical exercises on the psychological well-being of patients with multiple sclerosis: A comparative analysis. Adv Clin Exp Med. 2019 Nov;28(11):1477-1483. doi: 10.17219/acem/104529.Background
Bouzigon R, Grappe F, Ravier G, Dugue B. Whole- and partial-body cryostimulation/cryotherapy: Current technologies and practical applications. J Therm Biol. 2016 Oct;61:67-81. doi: 10.1016/j.jtherbio.2016.08.009. Epub 2016 Aug 27.Background
Radecka A, Knyszynska A, Luczak J, Lubkowska A. Adaptive changes in muscle activity after cryotherapy treatment: Potential mechanism for improvement the functional state in patients with multiple sclerosis. NeuroRehabilitation. 2021;48(1):119-131. doi: 10.3233/NRE-201535.Background
Zielinska-Nowak E, Wlodarczyk L, Kostka J, Miller E. New Strategies for Rehabilitation and Pharmacological Treatment of Fatigue Syndrome in Multiple Sclerosis. J Clin Med. 2020 Nov 7;9(11):3592. doi: 10.3390/jcm9113592.Background
Miller E, Kostka J, Wlodarczyk T, Dugue B. Whole-body cryostimulation (cryotherapy) provides benefits for fatigue and functional status in multiple sclerosis patients. A case-control study. Acta Neurol Scand. 2016 Dec;134(6):420-426. doi: 10.1111/ane.12557. Epub 2016 Jan 18.
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History
Started
Sept 2022
Main results due
Jun 2024
Finished
Jul 2025