Investigation Of The Effects Of Proprioceptive Neuromuscular Facilitation Techniques For Upper Extremity And Trunk, Combined With Respiration, On Respiratory Capacity And Swallowing In Individuals With Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT05342025

We could not find results for this trial

What it found

No results found

We found no results in the registry or in papers.

This trial finished 3 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • PNF

Compared with

  • Breathing exercises

What it measured

Main measures

  • Forced expiratory volume 1st second

    8 weeks

  • Peak cough flow

    8 weeks

  • Respiratory muscle strength

    8 weeks

    Physical function
  • Forced vital capacity

    8 weeks

Other measures (5)

  • 2 Minutes Walking Test

    8 weeks

    Walking and mobility
  • Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL)

    8 weeks

    Quality of life (reported by participants)
  • Eating Assessment Tool (EAT-10)

    8 weeks

  • Fatigue Severity Scale (Fatigue Severity Scale)

    8 weeks

    Fatigue
  • Dysphagia Rating Scale in Multiple Sclerosis (DYMUS)

    8 weeks

Who could take part

MS (type not specified) · 25 to 55 · EDSS 1 to 5

Show the full criteria

Inclusion criteria

* Between the ages of 25-55, * MS was diagnosed by a neurologist, * Expanded Disability Status Scale (EDSS) - Expanded Disability Status Scale (EDSS) score between 1-5, * Have not had an attack in the last 3 months, * Have not participated in any respiratory-based physiotherapy and rehabilitation program in the last 6 months, * Not having orthopedic problems, persistent neck pain and/or radiculopathy that would prevent them from participating in the study, * Individuals willing to participate in the study will be included.

Exclusion criteria

* Having chest wall deformity, * Having chronic cardiac or pulmonary disease such as COPD, asthma, interstitial lung disease and heart failure that may affect respiratory muscle strength and respiratory functions, * Having pneumonia due to viral or bacterial infection in the last 6 months, * Having COVID-19, * Having a diagnosed psychiatric disorder, * Using tobacco and tobacco products, * Individuals with cooperation problems that may hinder assessments and treatment will not be included.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Multiple Sclerosis (MS) is an autoimmune central nervous system disease characterized by inflammation, demyelination, and axonal degeneration. Clinical symptoms of the disease include fatigue, speech, breathing, and swallowing problems. Although respiratory issues are less common in patients with MS, pulmonary complications are among the most common causes of mortality and morbidity in the terminal period. Although it is known that expiratory and inspiratory respiratory muscle training is beneficial in MS disease, the protocols used are variable and there is no standard exercise protocol. Respiratory muscle training is one of the instrument-oriented techniques, and the issue of delivering these devices to each patient creates a cost disadvantage. It is foreseen that the preference for the PNF technique to be applied in combination with respiration in the project will enable the development of alternative treatment approaches in order to solve the researched problems in MS disease, which is a critical health problem. Proprioceptive Neuromuscular Facilitation (PNF) is defined as facilitating the responses of the neuromuscular mechanism by stimulating the proprioceptors. In the literature, there is no study examining the effectiveness of PNF on respiratory and swallowing functions in individuals with MS. The aim of the study is to investigate the effects of PNF application in combination with upper extremity and trunk patterns on respiratory and swallowing functions in patients with MS.

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History

    1. Started

      May 2022

    2. Main results due

      Nov 2022

    3. Finished

      Apr 2023

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