Physical Training for People With Parkinson's Disease and Multiple Scl
Physical Training for People With Parkinson's Disease and Multiple Sclerosis: Effect on Mind and Body
We could not find results for this trial
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- High Intensity Interval Training (HIIT)
- Continuous Aerobic Training (CAT)
- Movement Advice
What it measured
Main measures
Change in anxiety and depressive symptoms
Baseline (week 0), week 4, week 12, week 16
Mood and sleep
Other measures (24)
Change in disease severity
Baseline (week 0), week 4, week 12, week 16
Disability progressionChange in cognitive function (i.e., ability to inhibit cognitive interference)
Baseline (week 0), week 4, week 12, week 16
Thinking and memoryChange in cognitive function (i.e., mental flexibility)
Baseline (week 0), week 4, week 12, week 16
Thinking and memoryChange in cognitive function (i.e., range of cognitive operations: motor speed, attention, and visuoperceptual functions)
Baseline (week 0), week 4, week 12, week 16
Thinking and memoryChange in fatigue
Baseline (week 0), week 4, week 12, week 16
FatiguePhysical functionChange in sleep quality
Baseline (week 0), week 4, week 12, week 16
Mood and sleepChange in well-being
Baseline (week 0), week 4, week 12, week 16
Change in quality of life
Baseline (week 0), week 4, week 12, week 16
Quality of life (reported by participants)Change in motor capacity (i.e., walking speed)
Baseline (week 0), week 4, week 12, week 16
Walking and mobilityChange in motor capacity (i.e., lower extremity function, mobility, and fall risk)
Baseline (week 0), week 4, week 12, week 16
Walking and mobility
Who could take part
Progressive MS · 18 and over
Show the full criteria
Inclusion criteria
* Diagnosis of Parkinson's Disease (PD) or Progressive Multiple Sclerosis (MS) * Hoehn \& Yahr stage \<4 (PD), Expanded Disability Status Scale score \<6 (MS) * Anxiety and/or depressive symptoms; Hospital Anxiety and Depression Scale (HADS) score >=8 points on HADS-A and/or HADS-D * Sufficient cognitive ability to understand training instructions; Montreal Cognitive Assessment score >21 points * Able to participate in intensive physical training, no contra-indications for exercise * Stable medication regime for at least 4 weeks prior to inclusion * Age >=18 years
Exclusion criteria
* Participation in intensive exercise program in the month prior to inclusion * Relapse in the month prior to inclusion (MS) * Symptoms indicating cardiovascular, pulmonary, or metabolic disease or cardiovascular, pulmonary, or metabolic disease which are not under control with medication * abnormal electrocardiography in rest
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
People with Parkinson's disease and Multiple Sclerosis experience disabling motor and non-motor symptoms, which respond insufficiently to medication. To adequately alleviate disease burden, physical training is increasing acknowledged as an assisting therapy; however, the optimal dose of exercise in unknown.
Papers
Loading reviews and guidelines…
History
Started
May 2022
Main results due
May 2025
Finished
Nov 2025