Interest of Immersive Virtual Reality on Stress During Botulinum Toxin
Interest of Immersive Virtual Reality on Stress During Botulinum Toxin Injections in Spasticity
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- DEEPSEN virtual reality mask
What it measured
Main measures
Heart rate variability (HRV) before injection and during the injections
during the procedure
Other measures (2)
Effect on the pain induced by the injection
during the procedure
PainQuality of the conditions for performing botulinum toxin injections
during the procedure
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* Adult patient, male or female, suffering from spasticity of neurological origin (multiple sclerosis, stroke, head trauma, etc.) and eligible for treatment by botulinum toxin injection * Able to give an informed consent to participate in research * Affiliation to Social Security.
Exclusion criteria
* Contraindication to virtual reality (epilepsy, schizophrenia, strabismus, amblyopia, anisometropia, local contraindication to wearing a helmet (lesion of the face or the skull) * Major cognitive disorders * Any medical condition deemed by the investigator to be incompatible with the research. * Indication of sedation by MEOPA during botulinum toxin injection sessions. * Patients who have already experienced virtual reality * Drug treatment or medical condition that may affect heart rate variability * Pregnant or breastfeeding women * Patients under safeguard of justice * Refusal of participation.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The main objective of the study is to investigate the effect of exposure to a virtual reality session during botulinum toxin injections on injection-induced stress. The secondary objectives are to study the effect of exposure to a virtual reality session during botulinum toxin injections, on the pain induced by the injection. And study the evolution of the effects of virtual reality with the repetition of the sessions.
Papers
Results
Musical intervention to reduce stress during botulinum toxin injection for spasticity: Protocol for a randomized controlled trial (MUSIBOT).PLoS One · 2025
Results
Use of immersive virtual reality for stress reduction during botulinum toxin injection for spasticity (RVTOX): a study protocol of a randomised control trial.BMJ Open · 2023
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History
Started
May 2022
Main results due
Dec 2024
Finished
Dec 2024