"Outwalk MS" - Benefits of Outdoor Walking in Multiple Sclerosis
"Outwalk MS" - Benefits of Outdoor Walking Exercise Therapy on Walking Capacity and Well-being in Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Walking exercise therapy
What it measured
Main measures
6-minutes walk test (6MWT)
Change from baseline (Pre) to after 7 weeks intervention (Post)
Walking and mobility
Other measures (19)
6-minutes walk test (6MWT)
Change from baseline (Pre) to 24 weeks follow-up (Follow-up)
Walking and mobilityTimed 25-foot walk test (T25FWT)
Change from baseline (Pre) to after 7 weeks intervention (Post)
Disability progressionWalking and mobilityTimed 25-foot walk test (T25FWT)
Change from baseline (Pre) to 24 weeks follow-up (Follow-up)
Disability progressionWalking and mobilitySix spot step test (SSST)
Change from baseline (Pre) to after 7 weeks intervention (Post)
Walking and mobilitySix spot step test (SSST)
Change from baseline (Pre) to 24 weeks follow-up (Follow-up)
Walking and mobility12-item multiple sclerosis walking scale (MSWS-12)
Change from baseline (Pre) to after 7 weeks intervention (Post)
Walking and mobilityQuality of life (reported by participants)12-item multiple sclerosis walking scale (MSWS-12)
Change from baseline (Pre) to 24 weeks follow-up (Follow-up)
Walking and mobilityQuality of life (reported by participants)Modified fatigue impact scale (MFIS)
Change from baseline (Pre) to after 7 weeks intervention (Post)
Thinking and memoryFatigueQuality of life (reported by participants)Modified fatigue impact scale (MFIS)
Change from baseline (Pre) to 24 weeks follow-up (Follow-up)
Thinking and memoryFatigueQuality of life (reported by participants)Falls-efficacy scale (FES-I)
Change from baseline (Pre) to after 7 weeks intervention (Post)
Walking and mobilityQuality of life (reported by participants)
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* ≥ 18 years * self-reported clinical MS diagnosis * PDDS ≤ 4 (corresponding to preserved walking capacity without assistive devices of at least 10 m) * able to independently attend the testing
Exclusion criteria
* self-reported comorbidities excluding participation in the intervention * recent (6 months retrospective) fractures, amputation or other critical physical impairments that eliminates participation in the described training study * participation in structured exercise therapy (including walking) for the past 3 months (≥ 2 session per week of moderate-to-high intensity)
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Deterioration of walking capacity is a common symptom in persons with multiple sclerosis (pwMS), furthermore having a negative influence on well-being. Studies have nevertheless shown that walking exercise therapy can improve walking capacity in pwMS. This may be particularly potent if occurring outdoors due to the varying stimuli it can provide (different surfaces and terrain etc.), and if the intensity and duration is adequate. Furthermore, outdoor walking is (1) suitable as a group intervention facilitating interaction between pwMS and (2) advantageous due to the health benefits offered through the interaction with nature itself. Both these aspects are also relevant for well-being. Few studies have nevertheless examined the effects of outdoor walking exercise therapy in pwMS. The purpose of the present study is therefore to examine the effects of 7 weeks of moderate-to-high intensity outdoor walking exercise therapy on walking capacity (primary outcome: 6-minute walk test) and well-being in pwMS.
Papers
Loading reviews and guidelines…
History
Started
Nov 2021
Main results due
Jul 2022
Finished
Nov 2022