Effect of the Vojta Therapy on Lipid Biomarkers Related to Myelin in Subjects With Multiple Sclerosis.

Status unknownNot a drug-phase studyMS (type not specified)NCT05558683

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Randomized clinical trial.

What it measured

Main measures

  • Respiratory function

    5 minutes

    Physical function
  • Spasticity

    10 minutes

    Spasticity
  • Balance

    10 minutes

    Walking and mobility
  • Age

    1 minutes

  • Time reaction

    5 minutes

Other measures (1)

  • Myelin

    15 minutes

    How the body handles the medicine

Who could take part

MS (type not specified) · 20 to 65

Show the full criteria

Inclusion criteria

* Persons with MS who have signed the informed consent. * Persons of both sexes. * Ages between 20 and 65 years. * Subjects of both sexes diagnosed with multiple sclerosis on the EDSS (Expanded Disability Status Scale).

Exclusion criteria

* Persons with multiple sclerosis with EDSS scale score equal to or greater than 7.0. * Occurrence of a flare during the period of the patient's participation in the study. * Pregnant women. * Oncology patients. * Non-acceptance and non-signing of informed consent. * Refusal to participate in the study. * Patients with severe cognitive impairment that does not allow them to understand the development of the study. * Patients with cardiovascular instability. * Patients who do not complete at least 75% of the scheduled sessions. Patients who do not present any of the contraindications contemplated for Vojta therapy.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Multiple sclerosis is the most common disabling neurological disease in young adults. Inflammation, demyelination, neurodegeneration, gliosis and repair processes are involved in its process, which are responsible for the heterogeneity and individual variability in the expression of the disease, the prognosis and the response to treatment. Clinically, MS manifests itself with the following symptoms: sensory focus, motor focus, spasticity, balance disorders, visual disturbances such as loss of vision or double vision or sphincter dysfunction. The main subtypes of MS are relapsing-remitting, secondary progressive, primary progressive, and progressive relapsing. Clinically, RRMS presents the initial inflammatory phase, characterized by reversible flares with neurological dysfunction, followed by periods of remission. Approximately 40-50% of these patients progress to SPMS, where the disease gradually progresses from intermittent flare-ups to steadily progressive worsening, resulting in permanent disability due to massive axonal loss. PPMS is the most severe subtype, affecting approximately 10% of all cases, and manifesting as progressive degeneration without any remission.

Papers

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History

    1. Started

      Dec 2022

    2. Main results due

      Jun 2023

    3. Finished

      Dec 2023

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