Examining a Wheelchair Exercise-training Intervention for Persons With
Feasibility and Initial Efficacy of a Wheelchair Exercise-training Intervention for Persons With Multiple Sclerosis
What it found
Results are posted in the registry, but without a statistical test of the main measure. See the numbers below.
What was tested
Treatment tested
- Seated Physical activity INtervention for persons with MS, "SPIN" program- Intervention Condition
Compared with
- WEllness for Longevity Living with MS (WELL)- Control Condition
Results by group
Study Feasibility: Number of Participants Recruited
16-weeks
| Group | Value | Interval | Number analysed |
|---|---|---|---|
| All Eligible Participants | 24 Participants | 24 |
Study Feasibility: Number of Participants Retained
16-weeks
| Group | Value | Interval | Number analysed |
|---|---|---|---|
| Exercise Training Intervention | 10 Participants | 12 | |
| Wellness Control | 10 Participants | 11 |
Exercise Training Intervention
Wellness Control
Study Feasibility: Number of Participants With Study-Related Adverse Events
16-weeks
| Group | Value | Interval | Number analysed |
|---|---|---|---|
| Exercise Training Intervention | 1 Participants | 12 | |
| Wellness Control | 0 Participants | 11 |
Exercise Training Intervention
Wellness Control
Values as posted on ClinicalTrials.gov. Outcomes measured differently across trials are not directly comparable.
Safety
| Group | Participants at risk | Serious adverse events | Deaths |
|---|---|---|---|
| Exercise Training Intervention | 12 | 0 (0.0%) | 0 |
| Wellness Control | 11 | 0 (0.0%) | 0 |
As posted on ClinicalTrials.gov. Serious adverse events include any serious health event during the trial, whether or not the treatment caused it.
What it measured
Main measures
Study Feasibility: Number of Participants Recruited
16-weeks
FeasibilityStudy Feasibility: Number of Participants Retained
16-weeks
FeasibilityStudy Feasibility: Number of Participants With Study-Related Adverse Events
16-weeks
SafetyFeasibility
Other measures (2)
Acceptability: Number of Participants With Positive Perceptions During Semi-Structured Interview
16-weeks
Quality of life (reported by participants)FeasibilityAcceptability as Measured by the Post-intervention Acceptability Survey
16-weeks
Feasibility
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* diagnosis of MS * self-reported use of a wheelchair (i.e., manual wheelchair, power wheelchair, or scooter) >50% of the time * age of 18 years or older * relapse free for the past 30 days * being non-active defined as not engaging in regular physical activity (30 minutes accumulated per day) on more than 2 days of the week during the previous 6 months (i.e., not meeting current physical activity guidelines for MS)
Exclusion criteria
* during telephone screening participants will complete an exercise pre-participation health screen and if participants report any symptoms or conditions contradictive of exercise then physician clearance will be required before enrollment
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The goal of this randomized controlled clinical trial is to examine the feasibility and initial efficacy of undertaking and delivering a novel, stakeholder-informed exercise training program for wheelchair users with multiple sclerosis. The main questions it aims to answer are: * Is the study feasible as measured by participant recruitment (24 participants total), retention (80%), and safety (adverse events)? * Is the study acceptable as measured by participant satisfaction and perceptions using an evaluation survey and semi-structured interviews? * Is there significant change in following the 16-week study in metabolic health outcomes, MS symptoms, and exercise behavior change? Participants will be randomized to complete the 16-week SPIN exercise training program or WellMS attention/contact wellness program. Researchers will compare the SPIN and WellMS groups to determine if there is a significant difference in metabolic health outcomes, MS symptoms, and exercise behavior change.
Papers
Loading reviews and guidelines…
History
Started
Jan 2024
Main results due
May 2025
Finished
May 2025
Results posted
Jan 2026