Plantar Sensitivity Training and Aerobic Exercise Training in Patients
Examination of the Implications of Plantar Sensitivity Training and Aerobic Exercise Training on Balance, Functional Capacity, Gait and Proprioception in Patients With Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- plantar sensitivity training
Given to everyone in the trial
- aerobic exercise training
What it measured
Main measures
Balance measurement (One-leg standing test(seconds))
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilityBalance measurement (measurement of spatiotemporal parameters of balance (with baropodometry) -Bipedal 30 seconds oscillation amplitude (mm)
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilityBalance measurement (measurement of spatiotemporal parameters of balance (with baropodometry)-Maximum oscillating amplitude (mm)
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilityBalance measurement (measurement of spatiotemporal parameters of balance (with baropodometry)-Average oscillation rate (mm/s)
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilitygait measurement (-timed 25-foot walk test)
Change from before treatment at 12 weeks of intervention/treatment
Disability progressionWalking and mobilitygait measurement(spatiotemporal parameters of gait (with baropodometry) -stride length (mm))
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilitygait measurement spatiotemporal parameters of gait (with baropodometry) -Bilateral maximum pressure (gr/cm2)
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilitygait measurement spatiotemporal parameters of gait (with baropodometry) -Bilateral mean pressure (gr/cm2)
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilitygait measurement (spatiotemporal parameters of gait (with baropodometry) -Right-left load distribution (%) (from five different points: 1st metatarsal head, 2nd-3rd metatarsal head, 4th-5th metatarsal head, heel medial, heel lateral)
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobility
Other measures (3)
functional capacity measurement
Change from before treatment at 12 weeks of intervention/treatment
Walking and mobilityproprioception measurement (-Ankle position sensation)
Change from before treatment at 12 weeks of intervention/treatment
proprioception measurement (-Sensation of ankle kinesthesia)
Change from before treatment at 12 weeks of intervention/treatment
Who could take part
MS (type not specified) · 18 to 65 · EDSS 3 to 5.5
Show the full criteria
Inclusion criteria
* being between the ages of 18-65 * Being diagnosed with multiple sclerosis according to McDonald's criteria * EDSS (Expanded Disability Status Scale) score between 3 and 5.5 * Stage 3/4/5 according to functional ambulation classification * Being able to ambulatory 100 meters independently or with device assistance * Not having an attack in the last 3 months * No change in routine treatment for MS (multiple sclerosis) in the past 3 months * Presence of plantar sensitivity loss (as measured with Semmes-Weinstein monofilaments) * having a plantar sensory threshold value higher than 2,83-3.61 for 1st metatarsal head; * 2.83-3.61 for 2-3rd metatarsal heads; * 2.83-3.61 for 4-5th metatarsal heads; * 3.61-4.08 for the lateral and medial heel)(15) * Decreased functional capacity (6-minute walking test distance F\<593±57meters, M\<638±44meters) (16)
Exclusion criteria
* Being diagnosed with pulmonary, orthopedic or cardiovascular disease * having diabetic neuropathy * Having neurological disease other than multiple sclerosis * Having a diagnosis of root compression, radiculopathy, lumbar disc herniation or complaining of low back pain for the last 3 months(17) * Using an ankle-foot orthosis (AFO) * Having cognitive dysfunction (MoCA score \<21)
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The aim of this thesis study is to examine whether plantar sensory training given in addition to aerobic exercise training has an additional contribution to balance, functional capacity, walking and proprioception in patients with multiple sclerosis. In this direction, the hypotheses of the study are stated below. H0 hypothesis: Plantar sensory training given in addition to aerobic exercise training in patients with multiple sclerosis has no additional contribution to balance, functional capacity, walking and proprioception. H1 hypothesis: Plantar sensory training given in addition to aerobic exercise training in patients with multiple sclerosis has an additional contribution to balance, functional capacity, walking and proprioception. Conventional exercises (with the addition of warm-up and cool-down periods) will be applied to all multiple sclerosis patients participating in the study; In addition, aerobic exercise training will be given. In addition to these exercises, plantar sensory training will be given to the sensory training group. Exercises and plantar sensory training will be given to the participants at intervals of three weeks, with progressively progressive sessions, 2 days a week for 12 weeks. Patients will be evaluated twice, before treatment and at the end of treatment 12 weeks later. Within the scope of the evaluation, balance, functional capacity, gait, proprioception and plantar sensory parameters will be measured in patients. As a result of the study, it will be examined whether plantar sensory training given in addition to aerobic exercise training in multiple sclerosis patients has an additional contribution to balance, functional capacity, walking and proprioception. There is no study in the literature examining the effects of plantar sensory training and aerobic exercise training on balance, functional capacity, walking and proprioception in patients with multiple sclerosis. In this respect, it is anticipated that the study will contribute to the literature.
Papers
Results
Homayuni A, Hosseini Z. Correction: An intervention design for promoting quality of life among patients with multiple sclerosis: a protocol with a planning approach for a mixed methods study. BMC Neurol. 2023 Feb 6;23(1):61. doi: 10.1186/s12883-023-03103-y. No abstract available.Results
Monaghan AS, Huisinga JM, Peterson DS. The relationship between plantar sensation and muscle onset during automatic postural responses in people with multiple sclerosis and healthy controls. Mult Scler Relat Disord. 2021 Nov;56:103313. doi: 10.1016/j.msard.2021.103313. Epub 2021 Oct 5.Results
Song Q, Zhang X, Mao M, Sun W, Zhang C, Chen Y, Li L. Relationship of proprioception, cutaneous sensitivity, and muscle strength with the balance control among older adults. J Sport Health Sci. 2021 Sep;10(5):585-593. doi: 10.1016/j.jshs.2021.07.005. Epub 2021 Jul 20.Results
Peebles AT, Bruetsch AP, Lynch SG, Huisinga JM. Dynamic Balance Is Related to Physiological Impairments in Persons With Multiple Sclerosis. Arch Phys Med Rehabil. 2018 Oct;99(10):2030-2037. doi: 10.1016/j.apmr.2017.11.010. Epub 2017 Dec 22.Results
Kalron A, Pasitselsky D, Greenberg-Abrahami M, Achiron A. Do textured insoles affect postural control and spatiotemporal parameters of gait and plantar sensation in people with multiple sclerosis? PM R. 2015 Jan;7(1):17-25. doi: 10.1016/j.pmrj.2014.08.942. Epub 2014 Aug 19.Results
Naka T, Hayashi T, Sugyo A, Watanabe R, Towatari F, Maeda T. The effects of lower extremity deep sensory impairments on walking capability in patients with incomplete cervical spinal cord injury. J Spinal Cord Med. 2022 Mar;45(2):287-292. doi: 10.1080/10790268.2020.1788879. Epub 2020 Jul 23.Results
Parsons SL, Mansfield A, Inness EL, Patterson KK. The relationship of plantar cutaneous sensation and standing balance post-stroke. Top Stroke Rehabil. 2016 Oct;23(5):326-32. doi: 10.1080/10749357.2016.1162396. Epub 2016 Mar 31.Results
Khalifeloo M, Naghdi S, Ansari NN, Akbari M, Jalaie S, Jannat D, Hasson S. A study on the immediate effects of plantar vibration on balance dysfunction in patients with stroke. J Exerc Rehabil. 2018 Apr 26;14(2):259-266. doi: 10.12965/jer.1836044.022. eCollection 2018 Apr.Results
Chisholm AE, Qaiser T, Williams AMM, Eginyan G, Lam T. Acquisition of a precision walking skill and the impact of proprioceptive deficits in people with motor-incomplete spinal cord injury. J Neurophysiol. 2019 Mar 1;121(3):1078-1084. doi: 10.1152/jn.00432.2018. Epub 2019 Feb 6.Results
Langeskov-Christensen M, Heine M, Kwakkel G, Dalgas U. Aerobic capacity in persons with multiple sclerosis: a systematic review and meta-analysis. Sports Med. 2015 Jun;45(6):905-23. doi: 10.1007/s40279-015-0307-x.
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History
Started
Sept 2023
Main results due
Jun 2024
Finished
Aug 2024