Effect of Neurodynamic Mobilization Exercises on Pain, Muscle Strength and Manual Dexterity in Multiple Sclerosis Patients

CompletedNot a drug-phase studyMS (type not specified)NCT06153264

We could not find results for this trial

What it found

No results found

We found no results in the registry or in papers.

This trial finished 2 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • neurodynamic mobilization exercise
  • strengthening exercises

What it measured

Main measures

  • Visual Analog Scale

    Baseline and after 6 weeks

    Pain
  • Leeds Assessment of Neuropathic Symptoms and Signs Scale

    Baseline and after 6 weeks

    Pain

Other measures (3)

  • Muscle strength

    Baseline and after 6 weeks

    Arm and hand functionPhysical function
  • Manual Ability Measure-36

    Baseline and after 6 weeks

    Arm and hand function
  • Nine hole peg test

    Baseline and after 6 weeks

    Arm and hand function

Who could take part

MS (type not specified) · 18 to 65

Show the full criteria

Inclusion criteria

1. Being diagnosed with MS according to McDonald 2010 diagnostic criteria 2. Being between the ages of 18-65 3. Volunteering to participate in the study

Exclusion criteria

1. Being under 18 years of age and over 65 years of age 2. Having a history of trauma within the last year 3. Having alcohol and substance addiction 4. Having diabetes mellitus 5. Having another known neurological disease 6. Being pregnant

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Current treatments for pain in MS patients include the use of non-pharmacological interventions such as electrotherapy and exercise, as well as pharmacological treatments. Neurodynamic mobilization exercises are an intervention that aims to restore homeostasis in and around the nervous system by activating the nervous system itself or the structures surrounding the nervous system. Neurodynamic mobilization facilitates movement between neural structures and their environment through manual techniques and exercise. Human and animal studies reveal that neurodynamic mobilization reduces intraneural edema, improves intraneural fluid distribution, reduces thermal and mechanical hyperalgesia, and reverses increased immune responses following a nerve injury.

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History

    1. Started

      Sept 2023

    2. Main results due

      Jun 2024

    3. Finished

      Jul 2024

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