The Effect of a Targeted Exercise Program on Balance and Postural Responses in Patients With Multiple Sclerosis (MS)

CompletedNot a drug-phase studyMS (type not specified)NCT06159361

We could not find results for this trial

What it found

No results found

We found no results in the registry or in papers.

This trial finished 2 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Balance targeted exercises

What it measured

Main measures

  • Change in balance ability as measured by the BESTest

    Baseline, 6 weeks (post intervention)

    Walking and mobility
  • Change in reaction time

    Baseline, 6 weeks (post intervention)

  • Change in movement velocity

    Baseline, 6 weeks (post intervention)

  • Change in endpoint excursion percentage

    Baseline, 6 weeks (post intervention)

  • Change in directional control percentage

    Baseline, 6 weeks (post intervention)

  • Change in maximum excursion percentage

    Baseline, 6 weeks (post intervention)

  • Change in muscle responses latency as measured by MCT

    Baseline, 6 weeks (post intervention)

    Myelin repair
  • Change in postural muscles responses latency as measured by Electromyography (EMG)

    Baseline, 6 weeks (post intervention)

    Myelin repair
  • Change in APA as measured by microvolts

    Baseline, 6 weeks (post intervention)

  • Change in CPA as measured by microvolts

    Baseline, 6 weeks (post intervention)

Other measures (2)

  • Change in balance confidence as measured by ABC

    Baseline, 6 weeks (post intervention)

    Walking and mobility
  • Change in quality of life as measured by the MSQoL-54

    Baseline, 6 weeks (post intervention)

    Quality of life (reported by participants)

Who could take part

MS (type not specified) · 18 to 70

Show the full criteria

Inclusion criteria

1. Must be18 to 70 years of age. 2. Medical diagnosis of MS confirmed by a neurologist. 3. Ability to stand independently without any aid for at least 3 minutes. 4. A Patients determined disease steps (PDDS) score of 5 or lower. 5. Normal or corrected-to-normal vision. 6. English or Spanish speaking.

Exclusion criteria

1. MS-related exacerbation or medication change in the past two months. 2. Presence of concurrent neurological or orthopedic disorders. 3. Unable to perform the experimental tasks.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The purpose of this study is to examine the effects of a postural adjustment, targeted training program on balance ability and postural responses anticipatory postural adjustments (APA) and compensatory postural adjustments (CPA) in individuals with MS

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History

    1. Started

      Dec 2023

    2. Main results due

      Sept 2024

    3. Finished

      Dec 2024

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