Effects of Cycling and Virtual Reality on Thinking Speed in Persons Wi
Effects of a Single Bout of Moderate Intensity Aerobic Cycling Exercise Combined With Virtual Reality on Processing Speed in Persons With Multiple Sclerosis and Mobility Disability
We could not find results for this trial
What it found
We found no results in the registry or in papers.
This trial finished 12 months ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- PACE-MS
What it measured
Main measures
Modified Flanker Task (MFT)
Immediately before the single bout of cycling and 5 minutes after the single bout of cycling.
Thinking and memory
Other measures (2)
Baseline mobility disability
Baseline visit only
Disability progressionWalking and mobilityBaseline Symbol Digit Modalities Test (SDMT)
Baseline visit only.
Thinking and memory
Who could take part
MS (type not specified) · 18 to 70
Show the full criteria
Inclusion criteria
* Speak English as their primary language * Confirmed MS diagnosis by a neurologist * Be relapse and steroid-free for at least 30 days * Mild-to-moderate self-report mobility disability
Exclusion criteria
* History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression) * Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q) * Currently use medications that may impact cognition (ex: steroids, benzodiazepines) * Currently pregnant * Severe cognitive impairment as measured by the Modified Telephone Interview of Cognitive Status (TICS-M) * No indication of age-related mild cognitive impairment or dementia, based on the MOCA-Blind (i.e., MOCA-Blind ≥19). * High likelihood of motion sickness * Regular cyclist, defined as cycling for at least 150 minutes/week
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).
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History
Started
Feb 2024
Main results due
Oct 2025
Finished
Oct 2025