Gut Microbiota Composition, Cognitive Function, and Physical Fitness i
Effect of Dance Classes on Gut Microbiota Composition, Cognitive Function, and Physical Fitness in Multiple Sclerosis Patients
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Dance classes
What it measured
Main measures
The shift in the mean gut microbiota diversity
Change from baseline at 3 months
Change from baseline in the mean quantitative mobility and leg function performance
Change from baseline at 3 months
Walking and mobilityChange from baseline in the mean quantitative upper extremity function performance
Change from baseline at 3 months
Disability progressionArm and hand functionDifferences in the mean quantitative maximal oxygen consumption
Changes from baseline at 3 months
Physical function
Who could take part
MS (type not specified) · 30 to 50
Show the full criteria
Inclusion criteria
* patients with multiple sclerosis, diagnosed according to official diagnostic criteria according to McDonald 2010 * Consent ability and written consent * The expanded disability status scale (EDSS) \<5.5 * age 30 - 50
Exclusion criteria
* serious comorbidities including psychiatric diseases * Significant cognitive impairment, clinically relevant or progressive disease (e.g., liver, kidney, cardiovascular system, respiratory tract, vascular system, brain, metabolism, thyroid) that could affect the course of the study * Clinically relevant addiction or substance abuse disorder (defined as alcohol, drug and drug abuse) * Nicotine consumption of > 5 cigarettes per day and no willingness to stop consumption during therapeutic fasting. * Simultaneous participation in an interventional study or participation in an interventional study in the last two months before study inclusion * Malignant disease * Insufficient mental possibility of cooperation Eating disorder
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The evidence suggests that multiple sclerosis (MS) induces a decline in motor and cognitive function and provokes a shift in gut microbiome composition in patients. Therefore, the purpose of this study is to explore the effect of a 12-week dance class training program on the gut microbiota composition, motor function, and cognitive function of patients with MS. The investigators will also study the following: * The impact of organised physical activity on quality of life * The impact of organised physical activity on body composition and metabolic parameters (e.g., insulin sensitivity, lipid profile, ect.) * The impact of organised physical activity on physical fitness (e.g., VO2max, Power, ect.)
Papers
Loading reviews and guidelines…
History
Started
Mar 2022
Main results due
Aug 2023
Finished
Dec 2023